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Protein Hook Homolog 3

Known as: HOOK3, h-hook3, hHK3 
Protein Hook homolog 3 (718 aa, ~83 kDa) is encoded by the human HOOK3 gene. This protein plays a role in the mediation of endocytosis.
National Institutes of Health

Related topics

Related topics

8 relations
Cellular MembraneCis Golgi networkCytoskeletonHOOK3 gene

Papers overview

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2018
2018
Overexpression of the CORVET complex alleviates the fungicidal effects of fludioxonil on the yeast Saccharomyces cerevisiae expressing hybrid histidine kinase 3
The hybrid histidine kinase 3 (HHK3) is a highly conserved sensor kinase in fungi that regulates the downstream HOG/p38 mitogen… 
2015
2015
High-Level HOOK3 Expression Is an Independent Predictor of Poor Prognosis Associated with Genomic Instability in Prostate Cancer
Hook microtubule-tethering protein 3 (HOOK3) is an adaptor protein for microtubule-dependent intracellular vesicle and protein… 
2015
2015
Hook Proteins: Association with Alzheimer Pathology and Regulatory Role of Hook3 in Amyloid Beta Generation
Defects in intracellular transport are implicated in the pathogenesis of Alzheimer’s disease (AD). Hook proteins are a family of… 
2013
2013
Gene Expression Analysis of the Brazilian Type of Hereditary Persistence of Fetal Hemoglobin: Identification of Genes that Could be Related to γ-Globin Activation
Increased γ-globin production and consequent fetal hemoglobin (Hb F, α2γ2) formation is an important modulator of the clinical… 
Highly Cited
2011
Highly Cited
2011
Chromosome rearrangement associated inactivation of tumour suppressor genes in prostate cancer.
Prostate cancer, the most common male cancer in Western countries, is commonly detected with complex chromosomal rearrangements… 
Highly Cited
2010
Highly Cited
2010
Hook3 Interacts with PCM1 to Regulate Pericentriolar Material Assembly and the Timing of Neurogenesis
Highly Cited
2009
Highly Cited
2009
SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans.
Expression of human tau in Caenorhabditis elegans neurons causes accumulation of aggregated tau leading to neurodegeneration and… 
2007
2007
The Microtubule-binding Protein Hook3 Interacts with a Cytoplasmic Domain of Scavenger Receptor A*
The class A scavenger receptor (SR-A) is a multifunctional transmembrane glycoprotein that is implicated in atherogenesis, innate… 
Highly Cited
2007
Highly Cited
2007
HOOK3-RET: a novel type of RET/PTC rearrangement in papillary thyroid carcinoma.
Chromosomal rearrangements of the RET proto-oncogene (RET/PTC) are the common feature of papillary thyroid carcinoma (PTC). In… 
2004
2004
IIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3
Innate immunity against intracellular pathogens is critically determined by an as yet unknown interferon (IFN)-inducible… 
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