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Protein Footprinting

Known as: Footprinting, Protein 
A method for determining points of contact between interacting proteins or binding sites of proteins to nucleic acids. Protein footprinting utilizes… 
National Institutes of Health

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Papers overview

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2011
2011
Myosin binding surface on actin probed by hydroxyl radical footprinting and site-directed labels.
Review
2010
Review
2010
Visualizing water molecules in transmembrane proteins using radiolytic labeling methods.
Essential to cells and their organelles, water is both shuttled to where it is needed and trapped within cellular compartments… 
2008
2008
Mapping cyclic nucleotide‐induced conformational changes in cyclicAMP receptor protein by a protein footprinting technique using different chemical proteases
CyclicAMP receptor protein (CRP) regulates transcription of numerous genes in Escherichia coli. Both cAMP and cGMP bind CRP, but… 
2007
2007
DNA and protein footprinting analysis of the modulation of DNA binding by the N-terminal domain of the Saccharomyces cerevisiae TATA binding protein.
Recombinant full-length Saccharomyces cerevisiae TATA binding protein (TBP) and its isolated C-terminal conserved core domain… 
2001
2001
Mapping DNA-binding sites of HIV-1 integrase by protein footprinting.
The HIV-1 integrase protein catalyzes integration of the viral genome into host cell DNA. Whereas the structures of the three… 
1999
1999
Ligand-induced Structural Alterations in Human Iron Regulatory Protein-1 Revealed by Protein Footprinting*
Human iron regulatory protein-1 (IRP-1) is a bifunctional protein that regulates iron metabolism by binding to mRNAs encoding… 
1998
1998
Mapping substrate-induced conformational changes in cAMP-dependent protein kinase by protein footprinting.
Upon binding of substrates the catalytic subunit (C) of cAMP-dependent protein kinase (cAPK) undergoes significant induced… 
1996
1996
Binding of the sigma 70 protein to the core subunits of Escherichia coli RNA polymerase, studied by iron-EDTA protein footprinting.
We have used a nonspecific protein cleaving reagent to map the interactions between subunits of the multisubunit enzyme RNA… 
1995
1995
Intermolecular Binding Sites of Human Immunodeficiency Virus Type 1 Rev Protein Determined by Protein Footprinting (*)
Human immunodeficiency virus encodes the regulatory protein Rev, which is required for expression of viral structural proteins… 
1991
1991
Mutations in 5S DNA and 5S RNA have different effects on the binding of Xenopus transcription factor IIIA.
The effects on TFIIIA binding affinity of a series of substitution mutations in the Xenopus laevis oocyte 5S RNA gene were… 
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