Protein Engineering

Known as: Engineering, Protein, Proteins, Genetic Engineering, Protein Genetic Engineering 
Procedures by which protein structure and function are changed or created in vitro by altering existing or synthesizing new structural genes that… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Software engineers are faced with a dilemma. They want to write general and wellstructured programs that are flexible and easy to… (More)
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Highly Cited
2002
Highly Cited
2002
Electrical signals produced by brain activity were first recorded from the cortical surface in animals by Richard Caton in 1875… (More)
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Highly Cited
2002
Highly Cited
2002
Through the study of single molecules it has become possible to explain the function of many of the complex molecular assemblies… (More)
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Highly Cited
1998
Highly Cited
1998
A protein semisynthesis method-expressed protein ligation-is described that involves the chemoselective addition of a peptide to… (More)
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Review
1998
Review
1998
Many small, monomeric proteins fold with simple two-state kinetics and show wide variation in folding rates, from microseconds to… (More)
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Review
1992
Review
1992
The theory, assumptions and limitations are outlined for a simple protein engineering approach to the problem of the stability… (More)
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Highly Cited
1990
Highly Cited
1990
In N-glycosylated glycoproteins, carbohydrate is attached to Asn in the sequence Asn-X-Ser/Thr, where X denotes any amino acid… (More)
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Highly Cited
1989
Highly Cited
1989
In the transition state for unfolding of barnase, the hydrophobic core between the major α-helix and β-sheet is somewhat weakened… (More)
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Highly Cited
1988
Highly Cited
1988
A biosynthetic antibody binding site, which incorporated the variable domains of anti-digoxin monoclonal antibody 26-10 in a… (More)
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Highly Cited
1986
Highly Cited
1986
Chimeric phage-plasmid expression vectors were constructed from pUC18/19 plasmids by cloning a single-stranded DNA (ssDNA) origin… (More)
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