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Genetic Engineering

Known as: Gene Splicing, Biotechnology, Genetic Engineering, engineering genetics 
Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The diversity, modularity, and efficacy of CRISPR-Cas systems are driving a biotechnological revolution. RNA-guided Cas enzymes… Expand
Highly Cited
2014
Highly Cited
2014
As immune-based therapies for cancer become potent, more effective, and more widely available, optimal management of their unique… Expand
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Highly Cited
2010
Highly Cited
2010
IntroductionIn breast cancer, gene expression analyses have defined five tumor subtypes (luminal A, luminal B, HER2-enriched… Expand
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Highly Cited
2009
Highly Cited
2009
Recombineering is an efficient method of in vivo genetic engineering applicable to chromosomal as well as episomal replicons in… Expand
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Review
2007
Review
2007
  • E. Kelly, S. Russell
  • Molecular therapy : the journal of the American…
  • 2007
  • Corpus ID: 20782641
Since the turn of the nineteenth century, when their existence was first recognized, viruses have attracted considerable interest… Expand
Highly Cited
2006
Highly Cited
2006
Through the adoptive transfer of lymphocytes after host immunodepletion, it is possible to mediate objective cancer regression in… Expand
Review
2003
Review
2003
Abiotic stresses, such as drought, salinity, extreme temperatures, chemical toxicity and oxidative stress are serious threats to… Expand
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Highly Cited
2000
Highly Cited
2000
The cytokine interleukin-10 (IL-10) has shown promise in clinical trials for treatment of inflammatory bowel disease (IBD). Using… Expand
Highly Cited
1990
Highly Cited
1990
Gene Splicing by Overlap Extension or "gene SOEing" is a PCR-based method of recombining DNA sequences without reliance on… Expand
Highly Cited
1989
Highly Cited
1989
Gene splicing by overlap extension is a new approach for recombining DNA molecules at precise junctions irrespective of… Expand