Propylthiouracil

Known as: 6-Propyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, 6-Propyl-2-thio-2,4(1H,3H)pyrimidinedione, 6-Propylthiouracil 
A thiourea derivative with antithyroid property. Propylthiouracil (PTU) interferes with the oxidation of iodine possibly by interaction with… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND The antithyroid drugs propylthiouracil and methimazole were introduced for clinical use about 60 yr ago and are… (More)
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Highly Cited
2009
Highly Cited
2009
 
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Highly Cited
2005
Highly Cited
2005
Individual differences in perception are ubiquitous within the chemical senses: taste, smell, and chemical somesthesis . A… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP), chemically related compounds, are probes for genetic… (More)
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Highly Cited
2002
Highly Cited
2002
Adult tasters of 6-n-propylthiouracil (PROP) are more sensitive to bitter taste and fattiness in foods, and often show lower… (More)
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Highly Cited
1998
Highly Cited
1998
The role of the deiodinases D1, D2, and D3 in the tissue-specific and time-dependent regulation of thyroid hormone bioactivity… (More)
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Highly Cited
1993
Highly Cited
1993
Vasculitis is a rare complication of propylthiouracil therapy. Antineutrophil cytoplasmic antibodies (ANCA) have been described… (More)
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Highly Cited
1991
Highly Cited
1991
The role of thyroid hormones in the testis is unclear, although recent evidence indicates they may be important for testicular… (More)
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1987
1987
Propylthiouracil has been shown experimentally to protect against alcohol-induced hepatocellular necrosis in hypoxic conditions… (More)
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Highly Cited
1979
Highly Cited
1979
Bitter taste thresholds for 6-n-propylthiouracil are bimodally distributed, dividing subjects into tasters and nontasters. Their… (More)
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