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Thiouracil
Known as:
4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo-
, Thiouracil [Chemical/Ingredient]
A sulfur-containing uracil. An established antithyroid drug and highly selective inhibitor of nitric oxide synthase (NOS), thiouracil also covalently…
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National Institutes of Health
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Related topics
Related topics
32 relations
Narrower (19)
1,3-dimethyl-4-thiouracil
2,4-dithiouracil
2-thio-4-hydrazinouracil
4,5-diamino-2-thiouracil
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Broader (6)
Antimetabolites
Antithyroid Agents
Uracil
Vasodilator Agents
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In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1980
Highly Cited
1980
Analysis of biological thiols: derivatization with monobromotrimethylammoniobimane and characterization by electrophoresis and chromatography.
R. C. Fahey
,
R. C. Fahey
,
+5 authors
E. Kosower
Analytical Biochemistry
1980
Corpus ID: 13592144
Highly Cited
1977
Highly Cited
1977
Clearance of chylomicron triacylglycerol and cholesteryl ester from the plasma of streptozotocin-induced diabetic and hypercholesterolemic hypothyroid rats.
T. Redgrave
,
D. A. Snibson
Metabolism: Clinical and Experimental
1977
Corpus ID: 46463784
Highly Cited
1969
Highly Cited
1969
Effects of prolactin and growth hormone on growth and metamorphosis of tadpoles of the frog, Rana pipiens.
P. S. Brown
,
B. Frye
General and Comparative Endocrinology
1969
Corpus ID: 11260947
Highly Cited
1969
Highly Cited
1969
Clinical application of serum-total-thyroxine estimation, resin uptake, and free-thyroxine index.
P. Howorth
,
N. F. Maclagan
The Lancet
1969
Corpus ID: 35679260
Highly Cited
1968
Highly Cited
1968
Changes in phospholipase A, lipase and cholesterol esterase activity in the aorta in experimental atherosclerosis in the rabbit and rat.
J. Atelski
,
D. Bowyer
,
A. Howard
,
G. Gresham
Journal of Atherosclerosis Research
1968
Corpus ID: 38137721
Highly Cited
1956
Highly Cited
1956
Cholesterol metabolism in the dog.
L. L. Abell
,
E. Mosbach
,
F. E. Kendall
Journal of Biological Chemistry
1956
Corpus ID: 5969545
Highly Cited
1951
Highly Cited
1951
The effect of thyroid deficiency induced by methyl thiouracil on the maturation of the central nervous system.
J. Eayrs
,
S. Taylor
Journal of Anatomy
1951
Corpus ID: 43788387
Thyroid hormone has a beneficial effect on body growth in the congenital cretin, but unless treatment is begun very early, it has…
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Highly Cited
1951
Highly Cited
1951
Inhibition of the Biosynthesis of Tobacco Mosaic Virus by Thiouracil
B. Commoner
,
F. Mercer
Nature
1951
Corpus ID: 2558790
SUBSTANCES capable of inhibiting specifically the formation of viruses are of obvious practical and theoretical interest. In the…
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Highly Cited
1947
Highly Cited
1947
THE MECHANISM OF IODINE CONCENTRATION BY THE THYROID GLAND: ITS NON-ORGANIC IODINE-BINDING CAPACITY IN THE NORMAL AND PROPYLTHIOURACIL-TREATED RAT
A. Taurog
,
I. Chaikoff
,
D. Feller
1947
Corpus ID: 1752697
Highly Cited
1946
Highly Cited
1946
Toxic manifestations of thiouracil therapy.
F. D. Moore
Journal of the American Medical Association
1946
Corpus ID: 43861200
Increasing evidence of the usefulness of thiouracil in the treatment of thyrotoxicosis 1 has been accompanied by the appearance…
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