Uracil

Known as: 4-hydroxy-2-(1H)-pyrimidione, 2,4(1H,3H)-Pyrimidinedione, 2,4-Pyrimidinediol 
A chemical compound that is used to make one of the building blocks of RNA. It is a type of pyrimidine.
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
BACKGROUND In a previous phase 3 trial of adjuvant chemotherapy after resection of non-small-cell lung cancer, a combination of… (More)
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Highly Cited
2003
Highly Cited
2003
Activation-induced cytidine deaminase (AID) is a 'master molecule' in immunoglobulin (Ig) class-switch recombination (CSR) and… (More)
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Review
2002
Review
2002
Uracil in DNA results from deamination of cytosine, resulting in mutagenic U : G mispairs, and misincorporation of dUMP, which… (More)
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Highly Cited
2002
Highly Cited
2002
A functional immune system depends on the production of a wide range of immunoglobulin molecules. Immunoglobulin variable region… (More)
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Highly Cited
1997
Highly Cited
1997
Folate deficiency causes massive incorporation of uracil into human DNA (4 million per cell) and chromosome breaks. The likely… (More)
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Highly Cited
1996
Highly Cited
1996
Precise mapping of DNA methylation patterns in CpG islands has become essential for understanding diverse biological processes… (More)
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Highly Cited
1994
Highly Cited
1994
An understanding of DNA methylation and its potential role in gene control during development, aging and cancer has been hampered… (More)
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Highly Cited
1990
Highly Cited
1990
Polymerase chain reactions (PCRs) synthesize abundant amplification products. Contamination of new PCRs with trace amounts of… (More)
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Highly Cited
1989
Highly Cited
1989
A series of yeast shuttle vectors and host strains has been created to allow more efficient manipulation of DNA in Saccharomyces… (More)
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Highly Cited
1985
Highly Cited
1985
  • T. A. Kunkel
  • Proceedings of the National Academy of Sciences…
  • 1985
Several single-base substitution mutations have been introduced into the lacZ alpha gene in cloning vector M13mp2, at 40-60… (More)
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