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Proinsulin

Known as: Proinsulin [Chemical/Ingredient] 
A pancreatic polypeptide of about 110 amino acids, depending on the species, that is the precursor of insulin. Proinsulin, produced by the PANCREATIC… 
National Institutes of Health

Related topics

Related topics

18 relations

Narrower (3)

(A-C-B) human proinsulinminiproinsulinproinsulin, des(31,32)-
Assay of ProinsulinINS geneIn BloodProcess of secretion

Broader (2)

InsulinProtein Precursors

Papers overview

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Highly Cited
1995
Highly Cited
1995
Improvement of serum lipids and blood pressure during intervention with n‐3 fatty acids was not associated with changes in insulin levels in subjects with combined hyperlipidaemia
Abstract. Objectives. To investigate the effect of an omega‐3 fatty acid concentrate K85 on serum lipids, lipoproteins, insulin… 
Highly Cited
1982
Highly Cited
1982
Lipid effects on the binding properties of a reconstituted insulin receptor.
Highly Cited
1982
Highly Cited
1982
Conversion of proinsulin to insulin: involvement of a 31,500 molecular weight thiol protease.
A lysed crude secretory granule fraction from rat islets of Langerhans was shown to process endogenous proinsulin to insulin with… 
Highly Cited
1978
Highly Cited
1978
The nuclear envelope. The major site of insulin binding in rat liver nuclei.
Highly Cited
1977
Highly Cited
1977
Control of juvenile diabetes mellitus and its relationship to endogenous insulin secretion as measured by C-peptide immunoreactivity.
Highly Cited
1977
Highly Cited
1977
Calcium antagonists and islet function--III. The possible site of action of verapamil.
Highly Cited
1974
Highly Cited
1974
Radioimmunoassay of human proinsulin C-peptide using synthetic human connecting peptide.
Radioimmunoassay of human C-peptide was established using antiserum to synthetic human connecting peptide and synthetic… 
Highly Cited
1973
Highly Cited
1973
A comparative study on the metabolism of human insulin and porcine proinsulin in man.
SUMMARY 1. The metabolism of unlabelled monocomponent human insulin and porcine proinsulin was studied in ten normal subjects… 
Highly Cited
1972
Highly Cited
1972
Effect of chronic sulfonylurea therapy on plasma insulin and proinsulin levels.
ABSTRACT The effect of the chronic administration of glyburide, a potent sulfonylurea, on plasma glucose, insulin and proinsulin… 
Highly Cited
1971
Highly Cited
1971
Studies on human proinsulin. Isolation and amino acid sequence of the human pancreatic C-peptide.
Abstract Human proinsulin C-peptide has been extracted from human pancreas with acid-ethanol and purified by means of gel… 
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