INS gene

Known as: INSULIN, Insulin Gene, INS-IGF2 SPLICED READ-THROUGH TRANSCRIPTS 
This gene plays a role in insulin and glucose regulation.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Loss-of-function mutations protective against human disease provide in vivo validation of therapeutic targets, but none have yet… (More)
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Highly Cited
2007
Highly Cited
2007
We report 10 heterozygous mutations in the human insulin gene in 16 probands with neonatal diabetes. A combination of linkage and… (More)
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Highly Cited
1997
Highly Cited
1997
Type 1 diabetes or insulin-dependent diabetes mellitus (IDDM) is due to autoimmune destruction of pancreatic β-cells. Genetic… (More)
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Highly Cited
1997
Highly Cited
1997
Type 1, or insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease associated with loss of tolerance to several… (More)
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Highly Cited
1996
Highly Cited
1996
Susceptibility to autoimmune insulin-dependent (type 1) diabetes mellitus is determined by a combination of environmental and… (More)
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Highly Cited
1995
Highly Cited
1995
The IDDM2 locus encoding susceptibility to type 1 diabetes was mapped previously to a 4.1–kb region spanning the insulin gene and… (More)
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Highly Cited
1993
Highly Cited
1993
A population association has consistently been observed between insulin-dependent diabetes mellitus (IDDM) and the "class 1… (More)
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Highly Cited
1990
Highly Cited
1990
Plasmids comprising transgene insertions in four lines of transgenic mice have been retrieved by plasmid rescue into a set of… (More)
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Highly Cited
1981
Highly Cited
1981
The length of a segment of DNA associated with the human insulin gene, which has been localized to the short arm of chromosome 11… (More)
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Highly Cited
1978
Highly Cited
1978
The complete amino acid sequence of human insulin-like growth factor I (IGF-I), a polypeptide isolated from serum, has been… (More)
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