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Procaine

Known as: ?-(diethylamino)ethyl p-aminobenzoate, Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, Procainum 
A benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby… 
National Institutes of Health

Related topics

Related topics

44 relations

Broader (4)

4-Aminobenzoic AcidAnalgesicsAnestheticsLocal Anesthetics

Narrower (24)

4-bromoacetamidoprocaineBenoxinateBretschneider cardioplegic solutionCardioplegin
In BloodPainPenicillin G procaine:Susc:Pt:Isolate:OrdQnPenicillins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Polymorphic acetylation of procaine amide in healthy subjects.
The acetylation of procaine amide has been studied by means of gas liquid chromatography in 33 healthy human volunteers. The… 
Highly Cited
1985
Highly Cited
1985
Evidence for a role for cellular alkalinization in the cyclic adenosine 3',5'-monophosphate-mediated initiation of motility in bovine caput spermatozoa.
Bicarbonate ion, the local anesthetics procaine and dibucaine, and the ionophores monensin and nigericin have been shown to… 
Highly Cited
1981
Highly Cited
1981
The inhibitory action of procaine, (+)-propranolol and (+/-)-propranolol on human sperm motility: antagonism by caffeine.
FAED, E.M. (1980). Decreased clearance of diflunisal in renal insufficiency-an alternative explanation. Br. J. clin. Pharmac., 10… 
1978
1978
Studies on High Molecular Weight Renin from Hog Kidney
Previous reports by several investigators on the activation of a high molecular weight renin have not been confirmed. A simple… 
1978
1978
Cardioplegic Solutions for Myocardial Preservation: Analysis of Hypothermic Arrest, Potassium Arrest, and Procaine Arrest
Separate effects of perfusion hypothermia, potassium arrest, and procaine arrest were studied in 150 hearts using the isolated… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
1968
1968
On the increase in rate of heat production caused by stretch in frog's skeletal muscle
1. The increase in rate of heat production caused by stretch in the unstimulated frog's sartorius (stretch response) has been… 
1958
1958
Successful treatment of quinidine and procaine amide intoxication; report of three cases.
EARLIER observations from this laboratory demonstrated in the laboratory animal the efficacy of molar sodium lactate in reversing… 
Highly Cited
1958
Highly Cited
1958
Absorption of local anesthetics.
Factors that determine the rate of absorption of a local anesthetic were studied in canine and, when possible, in human subjects… 
1949
1949
THE UTILITY OF INTRAVENOUS PEOCAINE IN THE ANESTHETIC MANAGEMENT OF CARDIAC DISTURBANCES