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Procaine

Known as: ?-(diethylamino)ethyl p-aminobenzoate, Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, Procainum 
A benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby… 
National Institutes of Health

Related topics

Related topics

44 relations

Broader (4)

4-Aminobenzoic AcidAnalgesicsAnestheticsLocal Anesthetics

Narrower (24)

4-bromoacetamidoprocaineBenoxinateBretschneider cardioplegic solutionCardioplegin
In BloodPainPenicillin G procaine:Susc:Pt:Isolate:OrdQnPenicillins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1991
Highly Cited
1991
A general model for the interaction of foreign molecules with lipid membranes: drugs and anaesthetics.
Highly Cited
1983
Highly Cited
1983
Removing the superior colliculus silences eye movements normally evoked from stimulation of the parietal and occipital eye fields
Highly Cited
1981
Highly Cited
1981
Activation of sea urchin eggs by microinjection of calcium buffers.
Highly Cited
1980
Highly Cited
1980
Free calcium changes associated with hormone action in amphibian oocytes.
Highly Cited
1978
Highly Cited
1978
The significance of multidose cardioplegia and hypothermia in myocardial preservation during ischemic arrest.
Highly Cited
1978
Highly Cited
1978
Effects of charged drugs on the phase transition temperatures of phospholipid bilayers.
Highly Cited
1977
Highly Cited
1977
The influence of membrane lipid composition and procaine on hyperthermic death of cells.
The mechanism of hyperthermic killing, a component of some cancer therapy, is not known. Cell-survival curves during hyperthermic… 
Highly Cited
1976
Highly Cited
1976
Uptake and release of calcium by rat brain synaptosomes
Highly Cited
1973
Highly Cited
1973
Long‐Term Use of Procaine Amide following Acute Myocardial Infarction
The safety of long-term prophylactic antiarrhythmic therapy with procaine amide was studied in 78 patients recovering from acute… 
Highly Cited
1972
Highly Cited
1972
NMR evidence for the hydrophobic interaction of local anaesthetics. Possible relation to their potency.
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