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Probable Transcription Factor PML
Known as:
Promyelocytic Leukemia Protein
, TRIM19
, Transcription Factor PML
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Protein PML (882 aa, ~98 kDa) is encoded by the human PML gene. This protein plays a role in both transcriptional regulation and PML body formation.
National Institutes of Health
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Related topics
Related topics
14 relations
DNA-Binding Proteins
Genes, Regulator
Negative Regulation of Cell Cycle
PML gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Compositional Control of Phase-Separated Cellular Bodies
Salman F. Banani
,
Allyson M. Rice
,
+4 authors
M. Rosen
Cell
2016
Corpus ID: 3193902
Review
2005
Review
2005
TRIM family proteins: retroviral restriction and antiviral defence
S. Nisole
,
J. Stoye
,
A. Saïb
Nature Reviews Microbiology
2005
Corpus ID: 21578514
Members of the tripartite motif (TRIM) protein family are involved in various cellular processes, including cell proliferation…
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Highly Cited
2002
Highly Cited
2002
Human SIR2 deacetylates p53 and antagonizes PML/p53‐induced cellular senescence
E. Langley
,
M. Pearson
,
+5 authors
T. Kouzarides
EMBO Journal
2002
Corpus ID: 14447603
The yeast Sir2 protein mediates chromatin silencing through an intrinsic NAD‐dependent histone deacetylase activity. Sir2 is a…
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Review
2002
Review
2002
Mechanisms of action of arsenic trioxide.
W. Miller
,
H. Schipper
,
Janet S. Lee
,
J. Singer
,
S. Waxman
Cancer Research
2002
Corpus ID: 1405160
Arsenic trioxide has shown substantial efficacy in treating both newly diagnosed and relapsed patients with acute promyelocytic…
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Review
2002
Review
2002
Alternative lengthening of telomeres in mammalian cells
J. Henson
,
A. Neumann
,
T. Yeager
,
R. Reddel
Oncogene
2002
Corpus ID: 20187617
Some immortalized mammalian cell lines and tumors maintain or increase the overall length of their telomeres in the absence of…
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Highly Cited
2000
Highly Cited
2000
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
M. Pearson
,
R. Carbone
,
+8 authors
P. Pelicci
Nature
2000
Corpus ID: 4403364
The tumour suppressor p53 induces cellular senescence in response to oncogenic signals. p53 activity is modulated by protein…
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Highly Cited
1999
Highly Cited
1999
Pml Is Critical for Nd10 Formation and Recruits the Pml-Interacting Protein Daxx to This Nuclear Structure When Modified by Sumo-1
A. M. Ishov
,
A. Sotnikov
,
+6 authors
G. Maul
Journal of Cell Biology
1999
Corpus ID: 656257
Nuclear domain 10 (ND10), also referred to as nuclear bodies, are discrete interchromosomal accumulations of several proteins…
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Highly Cited
1994
Highly Cited
1994
Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells
K. Weis
,
Sophie Rambaud
,
+5 authors
A. Dejean
Cell
1994
Corpus ID: 36801773
Highly Cited
1991
Highly Cited
1991
The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
H. Thé
,
C. Lavau
,
A. Marchio
,
C. Chomienne
,
L. Degos
,
A. Dejean
Cell
1991
Corpus ID: 40272758
Highly Cited
1991
Highly Cited
1991
Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
A. Kakizuka
,
W. Miller
,
+7 authors
R. Evans
Cell
1991
Corpus ID: 17351522
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