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Pregnenolone Carbonitrile

Known as: Pregnenolone Carbonitrile [Chemical/Ingredient], 16 alpha-Carbonitrile, Pregnenolone, Pregnenolone 16 alpha Carbonitrile 
A catatoxic steroid and microsomal enzyme inducer having significant effects on the induction of cytochrome P450. It has also demonstrated the… 
National Institutes of Health

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8 relations
In BloodPregnenolone Carbonitrile, (3 beta,16 beta)-Isomeragonistsanalogs & derivatives

Papers overview

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2005
2005
Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons
Neuroactive steroids can modulate brain excitability by interaction with several neurotransmitter receptor‐associated channels… 
1999
1999
Nano-electrospray tandem mass spectrometry for the analysis of neurosteroid sulphates.
Neurosteroids are synthesised in the central and peripheral nervous system or are derived from peripheral sources, and act in the… 
Highly Cited
1994
Highly Cited
1994
The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task
The neurosteroid pregnenolone sulfate (PS) has been recently shown to positively modulate NMDA receptors and to have memory… 
Highly Cited
1989
Highly Cited
1989
Human fetal and adult liver metabolism of ethylmorphine. Relation to immunodetected cytochrome P-450 PCN and interactions with important fetal corticosteroids.
Highly Cited
1984
Highly Cited
1984
Monoclonal antibodies to phenobarbital-induced rat liver cytochrome P-450.
Highly Cited
1979
Highly Cited
1979
Tissue distribution of the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat.
Abstract The tissue distribution of the receptor protein for 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) in adult male Sprague… 
1973
1973
Urinary steroid levels in newborn infants with intrauterine growth retardation.
Urinary steroid excretion of 6β-OH-cortisol (6β-OH-F), tetrahydrocortisone (THE), l6α-OH-pregnenolone (16α-0H-PG) and 16a-OH… 
Highly Cited
1970
Highly Cited
1970
Effect of ethanol metabolism on redox state of steroid sulphates in man.
Ethanol intake has been shown to cause a rapid increase of the concentration of androst-5-ene-3β,17β-diol 3-sulphate and a… 
1968
1968
Pathways for androgen biosynthesis from [7 alpha-3H] pregnenolone and [4-14C]progesterone by rat testis interstitium in vitro.
1945
1945
Effects on industrial production of the administration of Delta5 pregnenolone to factory workers.
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