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Pregnenolone Carbonitrile

Known as: Pregnenolone Carbonitrile [Chemical/Ingredient], 16 alpha-Carbonitrile, Pregnenolone, Pregnenolone 16 alpha Carbonitrile 
A catatoxic steroid and microsomal enzyme inducer having significant effects on the induction of cytochrome P450. It has also demonstrated the… 
National Institutes of Health

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8 relations
In BloodPregnenolone Carbonitrile, (3 beta,16 beta)-Isomeragonistsanalogs & derivatives

Papers overview

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1999
1999
Nano-electrospray tandem mass spectrometry for the analysis of neurosteroid sulphates.
Neurosteroids are synthesised in the central and peripheral nervous system or are derived from peripheral sources, and act in the… 
Highly Cited
1997
Highly Cited
1997
The regional brain distribution of the neurosteroids pregnenolone and pregnenolone sulfate following intravenous infusion
1995
1995
Dehydroepiandrosterone sulfate suppresses hippocampal recurrent inhibition and synchronizes neuronal activity to theta rhythm
Several neurosteroids have proconvulsant and memory‐en‐hancing properties and are potent modulators of the γ‐amino butyric acid… 
Highly Cited
1994
Highly Cited
1994
The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task
The neurosteroid pregnenolone sulfate (PS) has been recently shown to positively modulate NMDA receptors and to have memory… 
Highly Cited
1989
Highly Cited
1989
Human fetal and adult liver metabolism of ethylmorphine. Relation to immunodetected cytochrome P-450 PCN and interactions with important fetal corticosteroids.
Highly Cited
1985
Highly Cited
1985
Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome…
Highly Cited
1984
Highly Cited
1984
Monoclonal antibodies to phenobarbital-induced rat liver cytochrome P-450.
Highly Cited
1979
Highly Cited
1979
Tissue distribution of the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat.
Abstract The tissue distribution of the receptor protein for 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) in adult male Sprague… 
Highly Cited
1977
Highly Cited
1977
Cytosolic receptor for aryl hydrocarbon hydroxylase induction by polycyclic aromatic compounds. Evidence for structural and regulatory variants among established cell cultured lines.
Highly Cited
1970
Highly Cited
1970
Effect of ethanol metabolism on redox state of steroid sulphates in man.
Ethanol intake has been shown to cause a rapid increase of the concentration of androst-5-ene-3β,17β-diol 3-sulphate and a… 
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