Polycomb

The Drosophila gene Polycomb (Pc) encodes a transcriptional repressor required for the segment-specific repression of homeotic selector genes by… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Polycomb (PcG) regulation has been thought to produce stable long-term gene silencing. Genomic analyses in Drosophila and mammals… (More)
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Highly Cited
2010
Highly Cited
2010
Many proteins that respond to DNA damage are recruited to DNA lesions. We used a proteomics approach that coupled isotopic… (More)
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Highly Cited
2007
Highly Cited
2007
PRC2 is thought to be the histone methyltransferase (HMTase) responsible for H3-K27 trimethylation at Polycomb target genes. Here… (More)
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Highly Cited
2006
Highly Cited
2006
The mechanisms by which embryonic stem (ES) cells self-renew while maintaining the ability to differentiate into virtually all… (More)
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Highly Cited
2006
Highly Cited
2006
In Arabidopsis thaliana, the promotion of flowering by cold temperatures, vernalization, is regulated via a floral-repressive… (More)
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Review
2006
Review
2006
Polycomb group (PcG) proteins are conserved regulatory proteins that repress transcription of particular target genes in animals… (More)
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Highly Cited
1998
Highly Cited
1998
Early in Drosophila embryogenesis, gap gene products directly repress transcription of homeotic (HOX) genes and thereby delimit… (More)
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Highly Cited
1998
Highly Cited
1998
Genes of the Polycomb group (PcG) of Drosophila encode proteins necessary for the maintenance of transcriptional repression of… (More)
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Highly Cited
1992
Highly Cited
1992
The polycomb group (Pc-G) genes are responsible for maintaining the repressed state of homeotic genes during development. It has… (More)
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Highly Cited
1988
Highly Cited
1988
Two genes known to control the determination of segmental identity in Drosophila melanogaster are polycomb and antennapedia. To… (More)
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