Skip to search formSkip to main contentSkip to account menu

Poly(A)-specific ribonuclease

Known as: poly(A) ribonuclease (PAN), mRNA poly(A) nuclease, poly(A)ribonuclease 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Exoribonucleases
PARN gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.
2008
2008
Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode.
2007
2007
A Multifunctional RNA Recognition Motif in Poly(A)-specific Ribonuclease with Cap and Poly(A) Binding Properties*
Poly(A)-specific ribonuclease (PARN) is an oligomeric, processive and cap-interacting 3′ exoribonuclease that efficiently… 
2007
2007
The R3H domain stabilizes poly(A)-specific ribonuclease by stabilizing the RRM domain.
Highly Cited
2006
Highly Cited
2006
Inhibition of mRNA Deadenylation by the Nuclear Cap Binding Complex (CBC)*
Poly(A)-specific ribonuclease (PARN) is a cap-interacting and poly(A)-specific 3′-exoribonuclease. Here we have investigated how… 
2004
2004
Coordination of Divalent Metal Ions in the Active Site of Poly(A)-specific Ribonuclease*
Poly(A)-specific ribonuclease (PARN) is a highly poly(A)-specific 3′-exoribonuclease that efficiently degrades mRNA poly(A) tails… 
Highly Cited
2002
Highly Cited
2002
Identification of the Active Site of Poly(A)-specific Ribonuclease by Site-directed Mutagenesis and Fe2+-mediated Cleavage*
Poly(A)-specific ribonuclease (PARN) is the only mammalian exoribonuclease characterized thus far with high specificity for… 
2002
2002
Inhibition of Klenow DNA polymerase and poly(A)-specific ribonuclease by aminoglycosides.
Aminoglycosides are known to bind and perturb the function of catalytic RNA. Here we show that they also are potent inhibitors of… 
Highly Cited
2001
Highly Cited
2001
The mRNA Cap Structure Stimulates Rate of Poly(A) Removal and Amplifies Processivity of Degradation*
Poly(A)-specific ribonuclease (PARN) is an oligomeric, processive, and cap-interacting 3′ exonuclease. We have studied how the… 
Highly Cited
1997
Highly Cited
1997
Poly(A) Tail Shortening by a Mammalian Poly(A)-specific 3′-Exoribonuclease*
3′-Exonucleolytic removal of the poly(A) tail is the first and often rate-limiting step in the decay of many eucaryotic mRNAs. In… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)