PARN gene

Known as: DEADENYLATING NUCLEASE, DAN, deadenylation nuclease 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2016
024619752016

Papers overview

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2013
2013
MicroRNAs (miRNAs) are typically generated as ~22-nucleotide double-stranded RNAs via the processing of precursor hairpins by the… (More)
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2012
2012
PARN is one of several deadenylase enzymes present in mammalian cells, and as such the contribution it makes to the regulation of… (More)
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2010
2010
Poly(A)-specific ribonuclease (PARN) is a mammalian 3'-exoribonuclease that degrades poly(A) with high specificity. To reveal… (More)
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2007
2007
Poly(A)-specific ribonuclease (PARN) is an oligomeric, processive and cap-interacting 3' exoribonuclease that efficiently… (More)
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Highly Cited
2006
Highly Cited
2006
CUG-BP is the human homolog of the Xenopus EDEN-BP, which was shown previously to bind to mRNAs, such as c-mos, that exhibit… (More)
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Highly Cited
2006
Highly Cited
2006
Cytoplasmic polyadenylation is one mechanism that regulates translation in early animal development. In Xenopus oocytes… (More)
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Highly Cited
2003
Highly Cited
2003
Eukaryotic mRNA stability can be influenced by AU-rich elements (AREs) within mRNA primary sequences. Tristetraprolin (TTP) is a… (More)
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2003
2003
In Saccharomyces cerevisiae, a large complex, known as the Ccr4-Not complex, containing two nucleases, is responsible for mRNA… (More)
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2001
2001
Poly(A)-specific ribonuclease (PARN) is an oligomeric, processive, and cap-interacting 3' exonuclease. We have studied how the… (More)
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Highly Cited
2000
Highly Cited
2000
Poly(A) tail removal is often the initial and rate-limiting step in mRNA decay and is also responsible for translational… (More)
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