Exoribonucleases

Known as: Exoribonucleases [Chemical/Ingredient], exoribonuclease 
A family of enzymes that catalyze the exonucleolytic cleavage of RNA. It includes EC 3.1.13.-, EC 3.1.14.-, EC 3.1.15.-, and EC 3.1.16.-. EC 3.1.-
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
MicroRNAs (miRNAs) are endogenous noncoding small RNAs with important roles in many biological pathways; their generation and… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND MicroRNAs (miRNAs) are ~22 nucleotide (nt) small RNAs that control development, physiology, and pathology in animals… (More)
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Highly Cited
2009
Highly Cited
2009
The eukaryotic exosome is a ten-subunit 3′ exoribonucleolytic complex responsible for many RNA-processing and RNA-degradation… (More)
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Highly Cited
2008
Highly Cited
2008
microRNAs (miRNAs) play crucial roles in numerous developmental and metabolic processes in plants and animals. The steady-state… (More)
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Highly Cited
2007
Highly Cited
2007
Although the primary mechanism of eukaryotic messenger RNA decay is exoribonucleolytic degradation in the 5'-to-3' orientation… (More)
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Highly Cited
2006
Highly Cited
2006
EXORIBONUCLEASE4 (XRN4), the Arabidopsis thaliana homolog of yeast XRN1, is involved in the degradation of several unstable mRNAs… (More)
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Highly Cited
1997
Highly Cited
1997
We identified a complex in S. cerevisiae, the "exosome," consisting of the five essential proteins Rrp4p, Rrp41p, Rrp42p, Rrp43p… (More)
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Highly Cited
1997
Highly Cited
1997
Exoribonucleases are important enzymes for the turnover of cellular RNA species. We have isolated the first mammalian cDNA from… (More)
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Highly Cited
1997
Highly Cited
1997
XRN1 encodes an abundant cytoplasmic exoribonuclease, Xrn1p, responsible for mRNA turnover in yeast. A screen for bypass… (More)
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Highly Cited
1993
Highly Cited
1993
Analysis of the slowed turnover rates of several specific mRNA species and the higher cellular levels of some of these mRNAs in… (More)
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