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Pneumocandins

 
National Institutes of Health

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2012
2012
The anamorphic fungus Glarea lozoyensis mutant strain 74030 is an overproducer of pneumocandin B(0), which is chemically… Expand
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Highly Cited
1998
Highly Cited
1998
In addition to its potent efficacy in animal models against Candida sp., Aspergillus fumigatus, and Histoplasma capsulatum, the… Expand
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Highly Cited
1997
Highly Cited
1997
Pneumocandins and echinocandins are fungicidal antibiotics, currently in clinical development, that inhibit 1,3-beta-D-glucan… Expand
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1995
1995
The activities of the water-soluble pneumocandin derivatives L-733560, L-705589, and L-731373 were evaluated in mouse models of… Expand
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1995
1995
A new series of semisynthetic, water-soluble pneumocandin analogs has been found to be extremely potent against Pneumocystis… Expand
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1995
1995
The pneumocandins are semisynthetic analogs of echinocandin-like compounds that have shown efficacy in animal models of systemic… Expand
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1992
1992
A series of lipopeptide compounds co-produced during the fermentation of pneumocandin A0 (L-671,329) and related semisynthetic… Expand
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1992
1992
HPLC bioautography of the directed biosynthesis of Zalerion arboricola led to the discovery of pneumocandin B0 (L-688,786), a new… Expand
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1992
1992
Pneumocandin B0 (6) and six related lipopeptides are antifungal and anti-Pneumocystis carinii agents from mutants of Zalerion… Expand
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1992
1992
Zalerion arboricola ATCC 20868 produces pneumocandin A0 (L-671,329), a cyclic hexapeptide with a dimethylmyristic acid side chain… Expand
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