Phenolic aporphine-benzylisoquinoline alkaloids from Thalictrum faberi.
- L. Lin, S. Hu, G. Cordell
- ChemistryPhytochemistry
- 10 March 1999
A novel class of antitumor metabolites from the fungus Nattrassia Mangiferae
- M. Chu, I. Truumees, M. Puar
- Chemistry, Biology
- 28 February 1994
Structure elucidation of a new antifungal sterol sulfate, Sch 575867, from a deep-water marine sponge (Family: Astroscleridae).
- Shu-wei Yang, T. Chan, M. Chu
- ChemistryJournal of antibiotics (Tokyo. )
- 25 February 2003
It is described as a red-orange, rock hard, 15cm spherical sponge, with a thin veneer of living tissue over an aragonite skeleton, which is porous and smooth, with 2cm diameter mounds.
Chemokine receptor CCR-5 inhibitors produced by Chaetomium globosum.
- Shu-wei Yang, R. Mierzwa, M. Chu
- Chemistry, BiologyJournal of Natural Products
- 28 June 2006
Two novel chemokine receptor CCR-5 inhibitors were isolated from the fungal fermentation broth of Chaetomium globosum by normal- and reversed-phase HPLC purifications and the structure and relative configuration of 2 were determined unequivocally by X-ray crystallographic analysis.
Two novel diketopiperazines isolated from the fungus Tolypocladium sp.
- M. Chu, R. Mierzwa, M. Puar
- Chemistry, Biology
- 19 November 1993
A novel class of platelet activating factor antagonists from Phoma sp.
- M. Chu, I. Truumees, M. Puar
- Biology, ChemistryJournal of antibiotics (Tokyo. )
- 25 April 1993
Four novel platelet activating factor antagonists were isolated from the fermentation broth of the fungal culture, Phoma sp.
Isolation and structure elucidation of Sch 642305, a novel bacterial DNA primase inhibitor produced by Penicillium verrucosum.
- M. Chu, R. Mierzwa, A. McPhail
- ChemistryJournal of Natural Products
- 15 November 2003
A novel primase inhibitor, Sch 642305 (1), was isolated from the fermentation broth of the fungal culture Penicillium verrucosum and exhibited inhibitory activity against bacterial DNA primase enzyme with an EC(50) of 70 microM.
A new sterol sulfate, Sch 572423, from a marine sponge, Topsentia sp.
- Shu-wei Yang, Alexei Buivich, M. Chu
- BiologyBioorganic & Medicinal Chemistry Letters
- 19 May 2003
Sch 54445: a new polycyclic xanthone with highly potent antifungal activity produced by Actinoplanes sp.
- M. Chu, I. Truumees, M. Puar
- Chemistry, BiologyJournal of Natural Products
- 22 May 1997
As a broad-spectrum antifungal agent, Sch 54445 exhibits highly potent activities against various yeasts and dermatophytes with MIC values approximately 0.00038 microgram/mL.
Structure Elucidation of Sch 725674 from Aspergillus sp.
- Shu-wei Yang, T. Chan, J. Terracciano, D. Loebenberg, Mahesh Patel, M. Chu
- Chemistry, BiologyJournal of antibiotics (Tokyo. )
- 1 August 2005
The structure elucidation of 1 was accomplished based on extensive NMR spectroscopic analyses and showed inhibitory activity against Saccharomyces cerevisiae and Candida albicans with MICs of 8 and 32 µg/ml, respectively.
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