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Phosphodiesterase 4 Inhibitors

Known as: PDE 4 Inhibitors, Inhibitors, Phosphodiesterase 4, Phosphodiesterase Type 4 Inhibitors 
Compounds that specifically inhibit PHOSPHODIESTERASE 4.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Antipsychotic medications function through antagonism of D2 dopamine receptors. Blockade of D2 receptors causes an increase in… 
2004
2004
Behavioural effects of psychostimulant and opiate drugs are mediated in part by cAMP pathways operating in the nucleus accumbens… 
Review
2002
Review
2002
Phosphodiesterase 4 (PDE4) is a major cyclic adenosine-3',5'-monophosphate-metabolizing enzyme in immune and inflammatory cells… 
Highly Cited
2000
Highly Cited
2000
In a previous study, an up‐regulation of rolipram‐sensitive, low‐Km, cyclic AMP phosphodiesterase (PDE4) subtype PDE4A in rat… 
Review
2000
Review
2000
Phosphodiesterase 4 (PDE4) is a member of the growing family cyclic AMP and cyclic GMP. Earliest described inhibitors of PDE4… 
1999
1999
The objective of the present study was to assess the behavioural effects of rolipram, a specific cAMP phosphodiesterase (PDE4…