Rolipram

Known as: (R,S)-Rolipram, Rolipram [Chemical/Ingredient], (+/-)-Rolipram 
A phosphodiesterase 4 inhibitor with antidepressant properties.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
05010019792017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Resveratrol, a polyphenol in red wine, has been reported as a calorie restriction mimetic with potential antiaging and… (More)
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Highly Cited
2007
Highly Cited
2007
To support the role of DISC1 in human psychiatric disorders, we identified and analyzed two independently derived ENU-induced… (More)
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Highly Cited
2004
Highly Cited
2004
Evidence suggests that Alzheimer disease (AD) begins as a disorder of synaptic function, caused in part by increased levels of… (More)
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Highly Cited
2004
Highly Cited
2004
Although there is no spontaneous regeneration of mammalian spinal axons after injury, they can be enticed to grow if cAMP is… (More)
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Highly Cited
2004
Highly Cited
2004
Central neurons regenerate axons if a permissive environment is provided; after spinal cord injury, however, inhibitory molecules… (More)
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Highly Cited
2002
Highly Cited
2002
Pharmacological inhibition of type 4 cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase (PDE4) produces… (More)
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Highly Cited
2000
Highly Cited
2000
The specific type IV phosphodiesterase inhibitor rolipram is a potent suppressor of tumor necrosis factor-alpha (TNF) synthesis… (More)
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Highly Cited
1998
Highly Cited
1998
In an attempt to improve behavioral memory, we devised a strategy to amplify the signal-to-noise ratio of the cAMP pathway, which… (More)
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Highly Cited
1996
Highly Cited
1996
The present study demonstrates that chronic, but not acute, adminstration of several different classes of antidepressants… (More)
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Highly Cited
1995
Highly Cited
1995
In multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) the cytokines tumour necrosis… (More)
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