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Cilomilast

Known as: 4-cyano-4-(3-cyclopentoxy-4-methoxy-phenyl)-cyclohexane-1- carboxylic acid, Cilomilast [Chemical/Ingredient], Cis-4-Cyano-4-(3-(Cyclopentyloxy)-4-Methoxyphenyl)Cyclohexanecarboxylic Acid 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

ArifloSB 207499

Broader (3)

Cyclohexanecarboxylic AcidsNitrilesPhosphodiesterase 4 Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity.
Highly Cited
2012
Highly Cited
2012
Apremilast mechanism of action and application to psoriasis and psoriatic arthritis.
  • P. Schafer
  • Biochemical Pharmacology
  • 2012
  • Corpus ID: 19442410
Highly Cited
2009
Highly Cited
2009
Discovery of selective PDE4B inhibitors.
Review
2005
Review
2005
Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease
Review
2005
Review
2005
PDE4 inhibitors as new anti-inflammatory drugs: effects on cell trafficking and cell adhesion molecules expression.
Review
2004
Review
2004
PDE4 inhibitors in COPD--a more selective approach to treatment.
  • A. Vignola
  • Respiratory medicine
  • 2004
  • Corpus ID: 26159136
Review
2004
Review
2004
PDE4 inhibition: a novel approach for the treatment of inflammatory bowel disease.
Highly Cited
2003
Highly Cited
2003
Antiinflammatory effects of the phosphodiesterase-4 inhibitor cilomilast (Ariflo) in chronic obstructive pulmonary disease.
Cilomilast (Ariflo), a new oral phosphodiesterase-4 selective inhibitor, improves lung function in chronic obstructive pulmonary… 
Review
2001
Review
2001
The next generation of PDE4 inhibitors.
Highly Cited
2001
Highly Cited
2001
Anti-inflammatory and immunomodulatory potential of the novel PDE4 inhibitor roflumilast in vitro.
From a series of benzamide derivatives, roflumilast (3-cyclo-propylmethoxy-4-difluoromethoxy-N-[3,5-di-chloropyrid-4-yl… 
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