Cilomilast

Known as: 4-cyano-4-(3-cyclopentoxy-4-methoxy-phenyl)-cyclohexane-1- carboxylic acid, Cilomilast [Chemical/Ingredient], Cis-4-Cyano-4-(3-(Cyclopentyloxy)-4-Methoxyphenyl)Cyclohexanecarboxylic Acid 
 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Psoriasis and psoriatic arthritis are common clinical conditions that negatively impact health-related quality of life and are… (More)
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Review
2005
Review
2005
Inhibitors of phosphodiesterase type 4 (PDE4) act by increasing intracellular concentrations of cyclic AMP, which has a broad… (More)
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2005
2005
BACKGROUND Cilomilast and tacrolimus as well as rapamycin are potential drugs for the treatment of allergic skin diseases like… (More)
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2004
2004
Fibroblasts, as a major source of extracellular interstitial connective tissue matrix, play an important role in wound healing… (More)
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Highly Cited
2003
Highly Cited
2003
Cilomilast (Ariflo), a new oral phosphodiesterase-4 selective inhibitor, improves lung function in chronic obstructive pulmonary… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Inflammation in chronic obstructive pulmonary disease (COPD) is characterised by increased neutrophilic infiltration… (More)
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2002
2002
Tissue destruction, resulting in emphysema, can be a consequence of several pathologic processes. The current study evaluated the… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Chronic obstructive pulmonary disease (COPD) is a common, progressive respiratory disease that causes great morbidity… (More)
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Review
2001
Review
2001
Cilomilast (Ariflo, SB-207499) is an orally-active, second generation phosphodiesterase (PDE) inhibitor that may be effective in… (More)
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Highly Cited
2001
Highly Cited
2001
From a series of benzamide derivatives, roflumilast (3-cyclo-propylmethoxy-4-difluoromethoxy-N-[3,5-di-chloropyrid-4-yl… (More)
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