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Phenylethanolamine N-Methyltransferase
Known as:
Noradrenalin N-Methyltransferase
, Norepinephrine N Methyltransferase
, Noradrenaline N Methyltransferase
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A methyltransferase that catalyzes the reaction of S-adenosyl-L-methionine and phenylethanolamine to yield S-adenosyl-L-homocysteine and N…
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National Institutes of Health
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Related topics
Related topics
8 relations
In Blood
PNMT gene
Process of secretion
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholamine-synthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells.
H. Wong
,
Le Yu
,
Emily Y M Lam
,
E. K. Tai
,
W. Wu
,
C. Cho
Toxicology and Applied Pharmacology
2007
Corpus ID: 46094302
Highly Cited
2003
Highly Cited
2003
Homodimerization of the glucocorticoid receptor is not essential for response element binding: activation of the phenylethanolamine N-methyltransferase gene by dimerization-defective mutants.
M. Adams
,
O. Meijer
,
Jian Wang
,
A. Bhargava
,
D. Pearce
Molecular Endocrinology
2003
Corpus ID: 45888148
We have tested the commonly held hypothesis that glucocorticoid receptors (GRs) must dimerize via their DNA binding domain (DBD…
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Highly Cited
1995
Highly Cited
1995
Differential Activation of the Rat Phenylethanolamine N-Methyltransferase Gene by Sp1 and Egr-1 (*)
S. Ebert
,
D. L. Wong
Journal of Biological Chemistry
1995
Corpus ID: 2724301
The rat phenylethanolamine N-methyltransferase (PNMT) gene contains overlapping consensus elements for the Sp1 and Egr-1…
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Highly Cited
1992
Highly Cited
1992
Organization of amygdaloid projections to brainstem dopaminergic, noradrenergic, and adrenergic cell groups in the rat
D. M. Wallace
,
D. Magnuson
,
T. Gray
Brain Research Bulletin
1992
Corpus ID: 12271405
Highly Cited
1989
Highly Cited
1989
The amygdalo-brainstem pathway: Selective innervation of dopaminergic, noradrenergic and adrenergic cells in the rat
D. M. Wallace
,
D. Magnuson
,
T. Gray
Neuroscience Letters
1989
Corpus ID: 36327470
Highly Cited
1985
Highly Cited
1985
Distribution of neurons containing phenylethanolamine N‐methyltransferase in medulla and hypothalamus of rat
D. Ruggiero
,
C. Ross
,
Muhammed Anwar
,
Dong H. Park
,
T. Joh
,
D. Reis
The Journal of comparative neurology
1985
Corpus ID: 34127986
Neurons immunocytochemically labeled with the adrenaline‐synthesizing enzyme phenylethanolamine N‐methyltransferase were mapped…
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Highly Cited
1978
Highly Cited
1978
Changes in Central Catecholaminergic Neurons in the Spontaneously (Genetic) Hypertensive Rat
J. Saavedra
,
H. Grobecker
,
J. Axelrod
Circulation Research
1978
Corpus ID: 6771155
Catecholamines and catecholamine-synthesizing enzymes have been examined in specific brain areas during the development of…
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Review
1976
Review
1976
Regional distribution of adrenaline in rat brain
J. Gugten
,
M. Palkovits
,
H. Wijnen
,
D. Versteeg
Brain Research
1976
Corpus ID: 5272085
Highly Cited
1976
Highly Cited
1976
Studies on adrenal phenylethanolamine N- methyltransferase (PNMT) with S K & F 64139, a selective inhibitor.
R. Pendleton
,
C. Kaiser
,
G. Gessner
Journal of Pharmacology and Experimental…
1976
Corpus ID: 32062180
SK&F 64139 is a potent, reversible inhibitor of phenylethanolamine N-methyltransferase; its IC50 concentration in our standard…
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Highly Cited
1966
Highly Cited
1966
Control of enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids.
R. Wurtman
,
J. Axelrod
Journal of Biological Chemistry
1966
Corpus ID: 12447194
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