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Phenylethanolamine N-Methyltransferase

Known as: Noradrenalin N-Methyltransferase, Norepinephrine N Methyltransferase, Noradrenaline N Methyltransferase 
A methyltransferase that catalyzes the reaction of S-adenosyl-L-methionine and phenylethanolamine to yield S-adenosyl-L-homocysteine and N… Expand
National Institutes of Health

Related topics

Related topics

8 relations
In BloodPNMT geneProcess of secretionantagonists & inhibitors
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Epinephrine is required for normal cardiovascular responses to stress in the phenylethanolamine N-methyltransferase knockout mouse.
BACKGROUND Epinephrine (EPI) is an important neurotransmitter and hormone. Its role in regulating cardiovascular function at rest… Expand
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Highly Cited
2003
Highly Cited
2003
Homodimerization of the glucocorticoid receptor is not essential for response element binding: activation of the phenylethanolamine N-methyltransferase gene by dimerization-defective mutants.
We have tested the commonly held hypothesis that glucocorticoid receptors (GRs) must dimerize via their DNA binding domain (DBD… Expand
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2002
2002
Glucocorticoid responsiveness of the rat phenylethanolamine N-methyltransferase gene.
Two newly identified, overlapping (1 bp) glucocorticoid response elements (GREs) at -759 and -773 bp in the promoter of the rat… Expand
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Highly Cited
2001
Highly Cited
2001
Pheochromocytomas in von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2 display distinct biochemical and clinical phenotypes.
This study examined the mechanisms linking different biochemical and clinical phenotypes of pheochromocytoma in multiple… Expand
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1998
1998
Phenylethanolamine N-methyltransferase gene expression: synergistic activation by Egr-1, AP-2 and the glucocorticoid receptor.
The gene encoding the epinephrine synthesizing enzyme, phenylethanolamine N-methyltransferase (PNMT), is transcriptionally… Expand
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1995
1995
Differential activation of the rat phenylethanolamine N-methyltransferase gene by Sp1 and Egr-1.
The rat phenylethanolamine N-methyltransferase (PNMT) gene contains overlapping consensus elements for the Sp1 and Egr-1… Expand
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1994
1994
Egr-1 activation of rat adrenal phenylethanolamine N-methyltransferase gene.
The immediate early gene transcription factor Egr-1 increases luciferase reporter gene activity 3-4-fold when a rat… Expand
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Highly Cited
1986
Highly Cited
1986
Glucocorticoid receptor immunoreactivity in monoaminergic neurons of rat brain.
A monoclonal antibody against the rat liver glucocorticoid receptor was used in combination with rabbit antibodies against… Expand
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1985
1985
Distribution of neurons containing phenylethanolamine N-methyltransferase in medulla and hypothalamus of rat.
Neurons immunocytochemically labeled with the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase were mapped… Expand
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Highly Cited
1984
Highly Cited
1984
Tonic vasomotor control by the rostral ventrolateral medulla: effect of electrical or chemical stimulation of the area containing C1 adrenaline neurons on arterial pressure, heart rate, and plasma…
We have studied the responses to electrical and chemical stimulation of the ventrolateral medulla in the chloralose-anesthetized… Expand
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