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Phenylethanolamine N-Methyltransferase
Known as:
Noradrenalin N-Methyltransferase
, Norepinephrine N Methyltransferase
, Noradrenaline N Methyltransferase
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A methyltransferase that catalyzes the reaction of S-adenosyl-L-methionine and phenylethanolamine to yield S-adenosyl-L-homocysteine and N…
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National Institutes of Health
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Related topics
Related topics
8 relations
In Blood
PNMT gene
Process of secretion
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Transcriptional Regulation of Phenylethanolamine N‐Methyltransferase in Pheochromocytomas from Patients with von Hippel–Lindau Syndrome and Multiple Endocrine Neoplasia Type 2
Thanh T. Huynh
,
K. Pacak
,
+5 authors
G. Eisenhofer
Annals of the New York Academy of Sciences
2006
Corpus ID: 16375874
Abstract: Pheochromocytomas in multiple endocrine neoplasia type 2 (MEN‐2) express phenylethanolamine N‐methyltransferase (PNMT…
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2004
2004
Adrenal medullary function and expression of catecholamine-synthesizing enzymes in mice with hypothalamic obesity.
A. C. Martins
,
K. L. Souza
,
M. Shio
,
P. Mathias
,
P. Lelkes
,
R. M. G. Garcia
Life Science
2004
Corpus ID: 32562031
1996
1996
Role of Egr‐1 in Cholinergic Stimulation of Phenylethanolamine N‐Methyltransferase Promoter
K. Morita
,
D. L. Wong
Journal of Neurochemistry
1996
Corpus ID: 1838003
Abstract: The effects of the cholinergic agonist carbachol on phenylethanolamine N‐methyltransferase promoter activity and Egr‐1…
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1989
1989
Cellular substrates for interactions between neurons containing phenylethanolamine N‐methyltransferase and GABA in the nuclei of the solitary tracts
V. Pickel
,
J. Chan
,
T. Milner
The Journal of comparative neurology
1989
Corpus ID: 21061425
Adrenaline and γ‐aminobutyric acid (GABA) have been implicated in autonomic functions involving the intermediate and caudal…
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1988
1988
Synthesis and evaluation of 3-substituted analogues of 1,2,3,4-tetrahydroisoquinoline as inhibitors of phenylethanolamine N-methyltransferase.
G. L. Grunewald
,
D. J. Sall
,
J. Monn
Journal of Medicinal Chemistry
1988
Corpus ID: 40760017
1,2,3,4-Tetrahydroisoquinoline (THIQ) and aryl-substituted derivatives of THIQ are potent inhibitors of the enzyme that catalyzes…
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1987
1987
Inhibition of phenylethanolamine N-methyltransferase (PNMT) by aromatic hydroxy-substituted 1,2,3,4,-tetrahydroisoquinolines: further studies on the hydrophilic pocket of the aromatic ring binding…
D. J. Sall
,
G. L. Grunewald
Journal of Medicinal Chemistry
1987
Corpus ID: 22200399
In a continuation of studies directed toward characterizing the hydrophilic pocket within the aromatic ring binding region of the…
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1986
1986
Enkephalin and Neuropeptide Y: Two colocalized neuropeptides are independently regulated in primary cultures of bovine chromaffin cells
R. Pruss
,
É. Mezey
,
+4 authors
T. O'Donohue
Neuropeptides
1986
Corpus ID: 11764030
Highly Cited
1983
Highly Cited
1983
Effects of manipulating catecholamines on the incidence of the preovulatory surge of luteinizing hormone and ovulation in the rat: Evidence for a necessary involvement of hypothalamic adrenaline in…
C. Coen
,
M. Coombs
Neuroscience
1983
Corpus ID: 7132440
Highly Cited
1978
Highly Cited
1978
Changes in Central Catecholaminergic Neurons in the Spontaneously (Genetic) Hypertensive Rat
J. Saavedra
,
H. Grobecker
,
J. Axelrod
Circulation Research
1978
Corpus ID: 6771155
Catecholamines and catecholamine-synthesizing enzymes have been examined in specific brain areas during the development of…
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1978
1978
Studies on the distribution of phenylethanolamine N-methyltransferase and epinephrine in the rat.
R. Pendleton
,
G. Gessner
,
J. Sawyer
Research communications in chemical pathology and…
1978
Corpus ID: 31018466
Using two independent criteria, we have found the enzyme phenylethanolamine N-methyltransferase (PNMT) to be present in the…
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