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PNMT gene

Known as: PENT, PHENYLETHANOLAMINE N-METHYLTRANSFERASE, PNMT 
National Institutes of Health

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Related topics

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Phenylethanolamine N-Methyltransferase

Papers overview

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Highly Cited
2001
Highly Cited
2001
Existence of cardiac PNMT mRNA in adult rats: elevation by stress in a glucocorticoid-dependent manner.
Phenylethanolamine N-methyltransferase (PNMT) is the enzyme that synthesizes epinephrine from norepinephrine. The aim of this… 
2000
2000
Actions of hypoxia on catecholamine synthetic enzyme mRNA expression before and after development of adrenal innervation in the sheep fetus
1 We have investigated adrenal mRNA expression of the catecholamine synthetic enzymes tyrosine hydroxylase (TH) and… 
1999
1999
Tissue-specific alternative mRNA splicing ofphenylethanolamine n-methyltransferase (PNMT) duringdevelopment by intron RETENTIONfn1 fn1 Part ofthis work was presented in a poster session at the…
Highly Cited
1996
Highly Cited
1996
Effect of ring size or an additional heteroatom on the potency and selectivity of bicyclic benzylamine-type inhibitors of phenylethanolamine N-methyltransferase.
In the search for potent and selective inhibitors of the enzyme phenylethanolamine N-methyltransferase (PNMT; EC 2.1.1.28), we… 
1993
1993
The 5'-flanking region of the human dopamine beta-hydroxylase gene promotes neuron subtype-specific gene expression in the central nervous system of transgenic mice.
Highly Cited
1992
Highly Cited
1992
Quantitative analysis of bulbospinal projections from the rostral ventrolateral medulla: Contribution of C1‐adrenergic and nonadrenergic neurons
The contribution of C1‐adrenergic and nonadrenergic neurons to the spinal projection from the rostral ventrolateral medulla (RVLM… 
Highly Cited
1989
Highly Cited
1989
Role of glucocorticoids in the chromaffin-neuron developmental decision
Highly Cited
1988
Highly Cited
1988
Phenylethanolamine N-methyltransferase-containing terminals synapse directly on sympathetic preganglionic neurons in the rat
1988
1988
Synthesis and evaluation of 3-substituted analogues of 1,2,3,4-tetrahydroisoquinoline as inhibitors of phenylethanolamine N-methyltransferase.
1,2,3,4-Tetrahydroisoquinoline (THIQ) and aryl-substituted derivatives of THIQ are potent inhibitors of the enzyme that catalyzes… 
1984
1984
Brain epinephrine systems: detailed comparison of adrenergic and noradrenergic metabolism, receptor number and in vitro regulation, in two inbred rat strains
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