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Phenobarbital

Known as: Phenylethylbarbitursaeure, Phenylethylbarbiturate, 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl- 
A long-acting barbituric acid derivative with antipsychotic property. Phenobarbital binds to and activates the gamma-aminobutyric acid (GABA)-A… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (19)

1-methyl-5-phenyl-5-propylbarbituric acid2,4-dithiophenobarbital2-thiophenobarbital4-hydroxyphenobarbital
Airway ObstructionBelladonna Alkaloids 0.13 MG / Phenobarbital 16.2 MG Oral TabletChlorpheniramine / Ephedrine / Guaifenesin / Phenobarbital / TheophyllineDehydrocholate / homatropine / Phenobarbital

Broader (5)

BarbituratesCytochrome P-450 CYP2B6 InducersCytochrome P-450 CYP3A InducersHypnotics and Sedatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivo
A murine model of peritonitis was used to test the role of platelet/endothelial cell adhesion molecule 1 (PECAM-1/CD31) in acute… 
Highly Cited
1983
Highly Cited
1983
Intracellular pH regulation in the renal proximal tubule of the salamander. Basolateral HCO3- transport
We have used pH-, Na-, and Cl-sensitive microelectrodes to study basolateral HCO3- transport in isolated, perfused proximal… 
Highly Cited
1983
Highly Cited
1983
Differential effects of phenobarbitone and 3-methylcholanthrene induction on the hepatic microsomal metabolism and cytochrome P-450-binding of phenoxazone and a homologous series of its n-alkyl…
Highly Cited
1982
Highly Cited
1982
Microscopic analysis of ethanol damage to rat gastric mucosa after treatment with a prostaglandin.
Highly Cited
1982
Highly Cited
1982
Platelet‐derived growth factor is a chemoattractant for vascular smooth muscle cells
In previous experiments (Grotendorst et al, 1981), we showed that platelet‐derived growth factor promotes the migration of smooth… 
Highly Cited
1976
Highly Cited
1976
Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.
Highly Cited
1972
Highly Cited
1972
Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. II. Role of the cytochrome P-450 and P-448 fractions in drug and steroid…
Highly Cited
1971
Highly Cited
1971
A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide.
Highly Cited
1970
Highly Cited
1970
Interrelationships of chloride, bicarbonate, sodium, and hydrogen transport in the human ileum.
Using a triple-lumen constant perfusion system, the following observations were made in normal subjects. First, chloride… 
Highly Cited
1969
Highly Cited
1969
The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states.
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