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Phenobarbital

Known as: Phenylethylbarbitursaeure, Phenylethylbarbiturate, 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-phenyl- 
A long-acting barbituric acid derivative with antipsychotic property. Phenobarbital binds to and activates the gamma-aminobutyric acid (GABA)-A… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (19)

1-methyl-5-phenyl-5-propylbarbituric acid2,4-dithiophenobarbital2-thiophenobarbital4-hydroxyphenobarbital
Airway ObstructionBelladonna Alkaloids 0.13 MG / Phenobarbital 16.2 MG Oral TabletChlorpheniramine / Ephedrine / Guaifenesin / Phenobarbital / TheophyllineDehydrocholate / homatropine / Phenobarbital

Broader (5)

BarbituratesCytochrome P-450 CYP2B6 InducersCytochrome P-450 CYP3A InducersHypnotics and Sedatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Molecular basis of the effects of shear stress on vascular endothelial cells.
Highly Cited
1999
Highly Cited
1999
The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene*
The endogenous CYP2B6 gene becomes phenobarbital (PB) inducible in androstenol-treated HepG2 cells either transiently or stably… 
Highly Cited
1999
Highly Cited
1999
Phenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the CYP2B Gene
ABSTRACT The constitutively active receptor (CAR) transactivates a distal enhancer called the phenobarbital (PB)-responsive… 
Highly Cited
1999
Highly Cited
1999
Coronary Angioplasty with or without Stent Implantation for Acute Myocardial Infarction
Background Coronary-stent implantation is frequently performed for treatment of acute myocardial infarction. However, few studies… 
Highly Cited
1999
Highly Cited
1999
Lactobacillus species prevents colitis in interleukin 10 gene-deficient mice.
Highly Cited
1998
Highly Cited
1998
The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B Gene
ABSTRACT PBREM, the phenobarbital-responsive enhancer module of the cytochrome P-450 Cyp2b10 gene, contains two potential nuclear… 
Review
1992
Review
1992
Phenobarbital induction of cytochrome P-450 gene expression.
RESEARCH PAPERS' Proteins Generation of forms of fragment E with differing thrombin-binding properties during digestion of… 
Highly Cited
1985
Highly Cited
1985
Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.
Highly Cited
1975
Highly Cited
1975
Separation of subfragment-1 isoenzymes from rabbit skeletal muscle myosin
RABBIT skeletal muscle myosin is composed of two heavy chains and four light chains1. Two classes of light chains can be… 
Highly Cited
1953
Highly Cited
1953
TEXTBOOK OF GYNAECOLOGY
This is an outstanding book in the great French tradition. It is comprehensive, but throughout bears the stamp of personal… 
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