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Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.
The individual members of a homologous series of phenoxazone ethers related to ethoxyresorufin were O-dealkylated, and the parent compound phenoxazone was ring-hydroxylated, each at different ratesExpand
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver.
The O-dealkylations of ethoxyresorufin and pentoxyresorufin are widely used activity probes for measuring the cytochrome P450 forms, CYP1A1 and CYP2B1, respectively, and their induction byExpand
A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver
The expression of constitutive and inducible cytochrome P450 forms was measured in cynomolgus monkey liver and compared with man, rat, mouse and hamster. Four alkoxyresorufin O-dealkylation (AROD)Expand
2,5-hexanedione-induced testicular injury.
Now in its third decade of mechanistic investigation, testicular injury caused by 2,5-hexanedione (2,5-HD) exposure is a well-studied model with a rich database. The development of this modelExpand
Effects of ethynyl substituents on the electronic structure of cyclobutadiene.
The effects of ethynyl substitution on the electronic structure of cyclobutadiene are investigated in this work. Ethynyl substituted cyclobutadienes may be involved in Bergman cyclization reactionsExpand
ELECTRONIC STRUCTURE OF ETHYNYL SUBSTITUTED CYCLOBUTADIENES
We investigated the effects of ethynyl substitution on the e lectronic structure of cyclobutadiene. These species are i nvolved in Bergman Cyclization reactions a and are possible intermediates inExpand
Thermal Isomerizations of Diethynyl Cyclobutadienes and Implications for Fullerene Formation.
The mechanism by which carbon condenses to form PAHs or fullerenes is a problem that has garnered considerable theoretical and experimental attention. The ring-coalescence and annealing model for theExpand