Pharmacodynamic Study

Known as: PHARMACODYNAMIC 
A study of the biochemical and physiological effect of a drug and the mechanism of drug action and the relationship between drug concentration and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND The colony stimulating factor 1 receptor (CSF1R) ligands, CSF1 and interleukin-34, and the KIT ligand, stem cell… (More)
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2014
2014
THIOMAB™ drug conjugates (TDCs) with engineered cysteine residues allow site-specific drug conjugation and defined Drug-to… (More)
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Highly Cited
2005
Highly Cited
2005
In recent years, pharmacokinetic/pharmacodynamic (PK/PD) modeling has developed from an empirical descriptive discipline into a… (More)
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2002
2002
Purpose. To determine by pharmacodynamic (PD) analysis physiologically relevant parameters of the cellular kinetics of… (More)
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2001
2001
PURPOSE In the setting of target-based anticancer drug development, it is critical to establish that the observed preclinical… (More)
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Review
1999
Review
1999
Pharmacodynamic properties can be used to divide antibiotics into two major classes based on their mechanism of bactericidal… (More)
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1999
1999
This paper presents and illustrates methodology for specifying, estimating, and evaluating a predictive model for repeated… (More)
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1999
1999
BACKGROUND There are no adequate pharmacodynamic data relating concentrations of acetaminophen in serum to analgesia. METHODS… (More)
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1995
1995
Oral oltipraz, as a single-dose treatment, was evaluated as a chemopreventive agent in 31 normal subjects. In a subset of… (More)
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Review
1983
Review
1983
Calcium antagonistic drugs (also called slow channel or calcium channel inhibitors or calcium entry blockers) represent a major… (More)
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