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Pioglitazone: a review of its use in type 2 diabetes mellitus.
Pioglitazone is an antihyperglycaemic agent that, in the presence of insulin resistance, increases hepatic and peripheral insulin sensitivity, thereby inhibiting hepatic gluconeogenesis and… Expand
Rotigotine: in Parkinson's disease.
Rotigotine is a nonergolinic dopamine D3/D2/D1 receptor agonist delivered via a transdermal system and has been evaluated for the treatment of idiopathic Parkinson's disease. Patients with early… Expand
Abstract▴ Buprenorphine is a low molecular weight, lipophilic, opioid analgesic. Recently, a transdermal matrix patch formulation of buprenorphine has become available in three dosage strengths… Expand
SummaryAbstractPioglitazone is an antihyperglycaemic agent that, in the presence of insulin resistance, increases hepatic and peripheral insulin sensitivity, thereby inhibiting hepatic… Expand
Effect of repeated intradermal injections of heat‐inactivated Mycobacterium bovis bacillus Calmette–Guérin in adult asthma
- P. Shirtcliffe, S. Easthope, M. Weatherall, R. Beasley
- Clinical and experimental allergy : journal of…
- 1 February 2004
Background There are a number of reports in the Chinese medical literature from the last 30 years regarding the efficacy of repeated doses of heat‐inactivated bacillus Calmette–Guérin (BCG) in… Expand
Polyethylene glycol-liposomal doxorubicin: a review of its use in the management of solid and haematological malignancies and AIDS-related Kaposi's sarcoma.
UNLABELLED Polyethylene glycol (PEG)-liposomal doxorubicin is a formulation of the anthracycline doxorubicin in which the drug is encapsulated in PEG-coated liposomes. This alters the pharmacokinetic… Expand
Candesartan cilexetil: an update of its use in essential hypertension.
UNLABELLED Candesartan cilexetil is converted to the angiotensin II receptor antagonist candesartan during absorption from the gastrointestinal tract. The selective and competitive binding of… Expand
Spotlight on Gefitinib in Non-Small-Cell Lung Cancer
Gefitinib (Iressa™), the first commercially available epidermal growth factor receptor-tyrosine kinase (EGFR-TK) inhibitor, is indicated in the management of patients with locally advanced or… Expand
The effect of delipidated deglycolipidated (DDMV) and heat-killed Mycobacterium vaccae in asthma.
- P. Shirtcliffe, S. Easthope, +4 authors R. Beasley
- American journal of respiratory and critical care…
- 1 May 2001
Experimental and epidemiological evidence supports the hypothesis that exposure to mycobacteria has the potential to suppress the development of asthma and/or atopy and there are reports in the… Expand
Transdermal buprenorphine. Commentaries
○ Buprenorphine is a low molecular weight, lipophilic, opioid analgesic. Recently, a transdermal matrix patch formulation of buprenorphine has become available in three dosage strengths designed to… Expand