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Peroxisomal Bifunctional Enzyme

Known as: Peroxisomal Multifunctional beta-Oxidation Protein, L Bifunctional Enzyme, Peroxisomal Hydratase Dehydrogenase Epimerase 
A monomeric protein found in liver peroxisomes that contains two enzymatically active domains; an enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase… 
National Institutes of Health

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EHHADH geneIn BloodProcess of secretionantagonists & inhibitors

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EHHADH protein, human

Papers overview

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Highly Cited
2011
Highly Cited
2011
Organocatalytic direct asymmetric aldol reactions of 3-isothiocyanato oxindoles to ketones: stereocontrolled synthesis of spirooxindoles bearing highly congested contiguous tetrasubstituted…
The first example of a direct catalytic asymmetric intermolecular aldol reaction of 3-isothiocyanato oxindoles to simple ketones… 
Highly Cited
2009
Highly Cited
2009
Enantioselective intramolecular michael addition of nitronates onto conjugated esters: access to cyclic gamma-amino acids with up to three stereocenters.
A highly stereoselective synthesis of conformationally constrained cyclic gamma-amino acids has been devised. The key step… 
Highly Cited
2008
Highly Cited
2008
Imidazol-2-yl complexes of Cp*Ir as bifunctional ambident reactants.
Loss of chloride ion from imidazol-2-yl complex 4a activates the H-H bond of dihydrogen or the C-H bond of acetylene, forming an… 
Highly Cited
2006
Highly Cited
2006
Direct enantio- and diastereoselective Mannich reactions of malonate and beta-keto esters with N-Boc and N-Cbz aldimines catalysed by a bifunctional cinchonine derivative.
A highly enantioselective Mannich reaction between malonate esters and N-Boc and N-Cbz aldimines, catalysed by a bifunctional… 
Highly Cited
2005
Highly Cited
2005
Bifunctional AgOAc-catalyzed asymmetric [3 + 2] cycloaddition of azomethine ylides.
[reaction: see text] A bifunctional AgOAc-catalyzed asymmetric cycloaddition of azomethine ylides with electronic-deficient… 
Highly Cited
1997
Highly Cited
1997
The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism.
The dimeric, peroxisomal 3-ketoacyl-CoA thiolase catalyses the conversion of 3-ketoacyl-CoA into acyl-CoA, which is shorter by… 
1996
1996
Neuronal migration abnormality in peroxisomal bifunctional enzyme defect
Patterns of brain dysgenesis that resemble those in the Zellweger syndrome were demonstrated in a boy with an isolated defect of… 
Highly Cited
1993
Highly Cited
1993
Characterization of the structural requirements for assembly and nucleotide binding of an ATP-binding cassette transporter. The maltose transport system of Escherichia coli.
Highly Cited
1979
Highly Cited
1979
Gallium-68 labeling of albumin and albumin microspheres.
Because of the high stability constant of gallium transferrin, the formation of a protein that will be stable in vivo and labeled… 
Highly Cited
1978
Highly Cited
1978
Biological effects and repair of damage photoinduced by a derivative of psoralen substituted at the 3,4 reaction site: photoreactivity of this compound and lethal effect in yeast.
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