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Maltose/Maltodextrin System of Escherichia coli: Transport, Metabolism, and Regulation
  • W. Boos, H. Shuman
  • Medicine, Biology
    Microbiology and Molecular Biology Reviews
  • 1 March 1998
The maltose system of Escherichia coli offers an unusually rich set of enzymes, transporters, and regulators as objects of study, and basic issues that require clarification concerning the mechanism of MalT-mediated activation, repression by the transporter, biosynthesis and assembly of the outer membrane and inner membrane transporter proteins, and interrelationships between the mal enzymes and those of glucose and glycogen metabolism.
Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis
The crystal structure of this dimer showing two bound pyrophosphate molecules at 1.9 Å resolution is reported, and significant deviation from 2‐fold symmetry is seen at the interface of the dimer and in the regions corresponding to those residues known to be in contact with the translocation pore.
Trehalose synthesis genes are controlled by the putative sigma factor encoded by rpoS and are involved in stationary-phase thermotolerance in Escherichia coli
It is shown that the genes otsA, otsB, treA, and osmB, previously known to be osmotically regulated, are also induced during transition into stationary phase in a sigma S-dependent manner.
Archaeal Binding Protein-Dependent ABC Transporter: Molecular and Biochemical Analysis of the Trehalose/Maltose Transport System of the Hyperthermophilic Archaeon Thermococcus litoralis
The strong homology found between the components of this archaeal transport system and the bacterial systems is evidence for the evolutionary conservation of the binding protein-dependent ABC transport systems in these two phylogenetic branches.
Completion of the hook–basal body complex of the Salmonella typhimurium flagellum is coupled to FlgM secretion and fliC transcription
Results confirm that the flagellar regulatory hierarchy of S. typhimurium is temporally regulated after induction, and both FlgM secretion and class 3 gene expression occur upon completion of the hook–basal body structure.
Signal transduction between a membrane‐bound transporter, PtsG, and a soluble transcription factor, Mlc, of Escherichia coli
It is demonstrated that inactivation of MLC is achieved by sequestration of Mlc to membranes containing dephosphorylated Enzyme IICBGlc, which represents a novel form of signal transduction in gene regulation.
Evidence of recent lateral gene transfer among hyperthermophilic Archaea
Regulation of expression studies showed that the malE gene, located on the transposon, and the encoded trehalose/maltose‐binding protein (TMBP) are induced in the presence of maltose and tre Halose in both P. furiosus and T. litoralis, suggesting a possible mechanism for lateral gene transfer between Archaea or possibly between ArchaeA and Bacteria.
The activities of the Escherichia coli MalK protein in maltose transport, regulation, and inducer exclusion can be separated by mutations
The maltose regulon consists of several genes encoding proteins involved in the uptake and utilization of maltose and maltodextrins. Five proteins make up a periplasmic binding-protein-dependent
Glycerol facilitator of Escherichia coli: cloning of glpF and identification of the glpF product
It is shown that the gene encoding the facilitator, glpF, is the first gene in an operon with glpK, encoding glycerol kinase, at 88 min of the E. coli chromosome.
High-affinity maltose/trehalose transport system in the hyperthermophilic archaeon Thermococcus litoralis
It is concluded that maltose and trehalose are transported by the same high-affinity membrane-associated system, the first report on sugar transport in any hyperthermophilic archaeon.