Penicillamine

Known as: D Penicillamine, (S)-2-amino-3-mercapto-3-methylbutanoic acid, D-Valine, 3-mercapto- 
A beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, penicillamine chelates with heavy metals and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
OBJECTIVE The reported frequency of scleroderma M01-R renal crisis (SRC) in diffuse systemic sclerosis (SSc; scleroderma) is 15… (More)
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Highly Cited
2001
Highly Cited
2001
Excessive nitric oxide (NO) production in cytokine-activated beta cells has been implicated in beta cell disruption in type 1… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE To study the clinical implications of a skin thickness score > or =20 at first visit and of softening of… (More)
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE To test the hypothesis that systemic sclerosis (SSc) patients taking high-dose D-penicillamine (D-Pen) would have… (More)
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Highly Cited
1988
Highly Cited
1988
Parameters of fibrinolysis, including euglobulin fibrinolytic activity, tissue-type plasminogen activator (t-PA) antigen… (More)
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Highly Cited
1986
Highly Cited
1986
The cellular processes responsible for the proteinuria induced by the aminonucleoside of puromycin (PA) remain inadequately… (More)
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Highly Cited
1985
Highly Cited
1985
Endotoxin producing bacteria cause disseminated intravascular coagulation (DIC); however, the mechanism of endotoxin action in… (More)
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Highly Cited
1984
Highly Cited
1984
We determined the incidence of exercise-induced arterial hypoxaemia and its determinants in sixteen highly trained, healthy… (More)
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Highly Cited
1983
Highly Cited
1983
We have used the term supratype to describe combinations of alleles and have examined associations with disease. In RA and… (More)
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Highly Cited
1982
Highly Cited
1982
In a retrospective study on progressive systemic sclerosis, we compared 73 patients who had received D-penicillamine therapy for… (More)
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