Partitioning Defective 3 Homolog

Known as: Atypical PKC Isotype-Specific Interacting Protein, ASIP, PAR3-Alpha 
Partitioning defective 3 homolog (1356 aa, ~151 kDa) is encoded by the human PARD3 gene. This protein is involved in signal transduction, tight… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Despite the recent rapid growth in genome-wide data, much of human variation remains entirely unexplained. A significant… (More)
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Review
2009
Review
2009
The genetic basis underlying normal variation in the pigmentary traits of skin, hair and eye colour has been the subject of… (More)
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Highly Cited
2008
Highly Cited
2008
Fair color increases risk of cutaneous melanoma (CM) and basal cell carcinoma (BCC). Recent genome-wide association studies have… (More)
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Highly Cited
2008
Highly Cited
2008
We present results from a genome-wide association study for variants associated with human pigmentation characteristics among 5… (More)
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Highly Cited
2007
Highly Cited
2007
Human skin pigmentation shows a strong positive correlation with ultraviolet radiation intensity, suggesting that variation in… (More)
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Highly Cited
2003
Highly Cited
2003
Melanistic coat coloration occurs as a common polymorphism in 11 of 37 felid species and reaches high population frequency in… (More)
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Highly Cited
2002
Highly Cited
2002
The mammalian protein ASIP/PAR-3 interacts with atypical protein kinase C isotypes (aPKC) and shows overall sequence similarity… (More)
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Highly Cited
2001
Highly Cited
2001
The establishment and maintenance of cellular polarity are critical for the development of multicellular organisms. PAR… (More)
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Highly Cited
1997
Highly Cited
1997
In mouse follicular melanocytes, the switch between eumelanin and pheomelanin synthesis is regulated by the extension locus… (More)
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Highly Cited
1994
Highly Cited
1994
Apphcation Specific Instruction set Processors (A SIPS) are field or mask programmable processors of which the architecture and… (More)
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