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Pancreatic Endocrine Carcinoma

Known as: Islet cell carcinoma, Malignant Pancreatic Endocrine Tumor, High Grade Pancreatic Neuroendocrine Carcinoma 
An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. The mitotic count is… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Multiple angiogenesis inhibitors have been therapeutically validated in preclinical cancer models, and several in clinical trials… Expand
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Highly Cited
2007
Highly Cited
2007
BackgroundWe examine the epidemiology, natural history, and prognostic factors that affect the duration of survival for islet… Expand
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Highly Cited
2005
Highly Cited
2005
PURPOSE Pertuzumab, a recombinant humanized monoclonal antibody (2C4), binds to extracellular domain II of the HER-2 receptor and… Expand
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Highly Cited
2004
Highly Cited
2004
PURPOSE The role of systemic chemotherapy in the management of pancreatic endocrine carcinoma (islet cell carcinoma; PEC) is an… Expand
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Highly Cited
2004
Highly Cited
2004
In a transgenic mouse model expressing SV40 T Ag (Tag) as a de novo tumor Ag, immune surveillance fails and islet cell carcinomas… Expand
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Highly Cited
2002
Highly Cited
2002
The Eph family of receptor tyrosine kinases and their ligands, known as ephrins, play a crucial role in vascular development… Expand
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Highly Cited
2002
Highly Cited
2002
A number of recent preclinical studies have sparked interest in the concept of exploiting conventional chemotherapeutic drugs as… Expand
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Highly Cited
1998
Highly Cited
1998
Transgenic mice expressing the oncogene SV40 T antigen (Tag) in the insulin-producing beta cells of the pancreas develop islet… Expand
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Highly Cited
1996
Highly Cited
1996
Angiogenesis is activated during multistage tumorigenesis prior to the emergence of solid tumors. Using a transgenic mouse model… Expand
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Highly Cited
1991
Highly Cited
1991
Forty-five patients with metastatic neuroendocrine tumors were treated with a regimen of etoposide 130 mg/m2/d for 3 days plus… Expand
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