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Pancreatic Endocrine Carcinoma

Known as: Islet cell carcinoma, Malignant Pancreatic Endocrine Tumor, High Grade Pancreatic Neuroendocrine Carcinoma 
An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. The mitotic count is… 
National Institutes of Health

Related topics

Related topics

30 relations
Blood supply aspectsCDISC SEND Tumor Findings Results TerminologyClinical Data Interchange Standards Consortium TerminologyDacarbazine

Broader (4)

CarcinomaIslet Cell TumorMalignant neoplasm of pancreasPancreatic Neoplasm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
Tumor Cells Utilize Multiple Pathways to Down‐modulate Apoptosis: Lessons from a Mouse Model of Islet Cell Carcinogenesis
Apoptosis, the process of programmed cell death, plays a critical role in many normal and pathological (disease) processes. 1 In… 
1992
1992
Phase II trial of chlorozotocin and fluorouracil in islet cell carcinoma: a Southwest Oncology Group study.
PURPOSE A phase II trial that used fluorouracil (5-FU) and chlorozotocin (CTZ) was performed in patients with metastatic islet… 
Highly Cited
1991
Highly Cited
1991
Detection of K-ras mutations in pancreatic and hepatic neoplasms by non-isotopic mismatched polymerase chain reaction.
Mutations within codon 12 leading to activation of Kirsten-ras (K-ras) genes occur in a wide variety of human tumors, but have… 
Highly Cited
1990
Highly Cited
1990
Islet cell carcinoma of the pancreas. A study of 98 patients
In 98 patients with histologically proved pancreatic islet cell carcinoma who were studied between 1950 and 1987, 55 had… 
1988
1988
Successful treatment with SMS 201-995 of Cushing's syndrome caused by ectopic adrenocorticotropin secretion from a metastatic gastrin-secreting pancreatic islet cell carcinoma.
Signs and symptoms of Cushing's syndrome developed rapidly after total gastrectomy in a 37-yr-old man with a metastatic gastrin… 
Review
1987
Review
1987
DTIC therapy in patients with malignant intra-abdominal neuroendocrine tumors.
Malignant intra-abdominal neuroendocrine tumors are rare; consequently, a standard chemotherapeutic protocol for patients with… 
1978
1978
Expression of human prostatic acid phosphatase in a pancreatic islet cell carcinoma.
The immunologic specificity of human prostatic acidphosphatase has been established by several previous investigations as well as… 
Highly Cited
1977
Highly Cited
1977
An Islet Cell Carcinoma Containing Glucagon and Insulin: Chronic Glucagon Excess and Glucose Homeostasis
Described here is a patient who had an islet cell carcinoma containing both glucagon (glucagonoma) and insulin (insulinoma… 
1975
1975
Multiple hormone producing islet cell carcinomas of the pancreas. A morphological and biochemical investigation.
1969
1969
Effects of Streptozotocin in a Patient with Islet Cell Carcinoma
Streptozotocin, a new antitumor agent with diabetogenie properties, was administered to a patient with functioning islet cell… 
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