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Pancreatic Endocrine Carcinoma
Known as:
Islet cell carcinoma
, Malignant Pancreatic Endocrine Tumor
, High Grade Pancreatic Neuroendocrine Carcinoma
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An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. The mitotic count is…
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National Institutes of Health
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Related topics
Related topics
30 relations
Blood supply aspects
CDISC SEND Tumor Findings Results Terminology
Clinical Data Interchange Standards Consortium Terminology
Dacarbazine
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Broader (4)
Carcinoma
Islet Cell Tumor
Malignant neoplasm of pancreas
Pancreatic Neoplasm
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
Tumor Cells Utilize Multiple Pathways to Down‐modulate Apoptosis: Lessons from a Mouse Model of Islet Cell Carcinogenesis
J. Hager
,
D. Hanahan
Annals of the New York Academy of Sciences
1999
Corpus ID: 24032505
Apoptosis, the process of programmed cell death, plays a critical role in many normal and pathological (disease) processes. 1 In…
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1992
1992
Phase II trial of chlorozotocin and fluorouracil in islet cell carcinoma: a Southwest Oncology Group study.
R. Bukowski
,
C. Tangen
,
+4 authors
T. Fleming
Journal of Clinical Oncology
1992
Corpus ID: 22498441
PURPOSE A phase II trial that used fluorouracil (5-FU) and chlorozotocin (CTZ) was performed in patients with metastatic islet…
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Highly Cited
1991
Highly Cited
1991
Detection of K-ras mutations in pancreatic and hepatic neoplasms by non-isotopic mismatched polymerase chain reaction.
Philip Stork
,
M. Loda
,
S. Bosari
,
B. Wiley
,
Karin Poppenhusen
,
H. Wolfe
Oncogene
1991
Corpus ID: 41975308
Mutations within codon 12 leading to activation of Kirsten-ras (K-ras) genes occur in a wide variety of human tumors, but have…
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Highly Cited
1990
Highly Cited
1990
Islet cell carcinoma of the pancreas. A study of 98 patients
S. Venkatesh
,
N. Ordóñez
,
+4 authors
N. Samaan
Cancer
1990
Corpus ID: 28083345
In 98 patients with histologically proved pancreatic islet cell carcinoma who were studied between 1950 and 1987, 55 had…
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1988
1988
Successful treatment with SMS 201-995 of Cushing's syndrome caused by ectopic adrenocorticotropin secretion from a metastatic gastrin-secreting pancreatic islet cell carcinoma.
S. Lamberts
,
H. Tilanus
,
A. Klooswijk
,
H. Bruining
,
A. J. van der Lely
,
F. de Jong
Journal of Clinical Endocrinology and Metabolism
1988
Corpus ID: 25609601
Signs and symptoms of Cushing's syndrome developed rapidly after total gastrectomy in a 37-yr-old man with a metastatic gastrin…
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Review
1987
Review
1987
DTIC therapy in patients with malignant intra-abdominal neuroendocrine tumors.
Altimari Af
,
K. Badrinath
,
Reisel Hj
,
R. Prinz
Surgery
1987
Corpus ID: 25778493
Malignant intra-abdominal neuroendocrine tumors are rare; consequently, a standard chemotherapeutic protocol for patients with…
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1978
1978
Expression of human prostatic acid phosphatase in a pancreatic islet cell carcinoma.
B. Choe
,
E. Pontes
,
N. Rose
,
M. Henderson
Investigative urology
1978
Corpus ID: 28869413
The immunologic specificity of human prostatic acidphosphatase has been established by several previous investigations as well as…
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Highly Cited
1977
Highly Cited
1977
An Islet Cell Carcinoma Containing Glucagon and Insulin: Chronic Glucagon Excess and Glucose Homeostasis
G. Boden
,
O. Owen
,
I. Rezvani
,
B. Elfenbein
,
K. E. Quickel
Diabetes
1977
Corpus ID: 31518430
Described here is a patient who had an islet cell carcinoma containing both glucagon (glucagonoma) and insulin (insulinoma…
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1975
1975
Multiple hormone producing islet cell carcinomas of the pancreas. A morphological and biochemical investigation.
Samuel Hamman
,
G. Sale
Human Pathology
1975
Corpus ID: 13320058
1969
1969
Effects of Streptozotocin in a Patient with Islet Cell Carcinoma
L. Sadoff
Diabetes
1969
Corpus ID: 29826796
Streptozotocin, a new antitumor agent with diabetogenie properties, was administered to a patient with functioning islet cell…
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