Skip to search formSkip to main contentSkip to account menu

Dacarbazine

Known as: Dakarbazin, Dacarbazinum, Dacarbazine - DTIC 
A drug that is used to treat Hodgkin lymphoma and malignant melanoma and is being studied in the treatment of other types of cancer. It attaches to… 
National Institutes of Health

Related topics

Related topics

40 relations

Broader (1)

Antineoplastic Agents, Alkylating

Narrower (12)

BELD protocolBiocarbazineDAV protocolDECAV protocol
Blood Coagulation DisordersCOPDAC RegimenCYVADIC protocolCyVADIC Regimen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1985
1985
1H NMR study of labile proton exchange in the heme cavity as a probe for the potential ligand entry channel in myoglobin.
The exchange rates of heme cavity histidine nitrogen-bound protons in horse and dog metcyanomyoglobins have been determined at 40… 
Highly Cited
1982
Highly Cited
1982
Binding of a calcium antagonist, [3H]nitrendipine, to high affinity sites in bovine aortic smooth muscle and canine cardiac membranes.
[(3)H]Nitrendipine, a potent calcium channel antagonist [3-ethyl-5-methyl-1-1,4-dihydro-2,6 - dimethyl - 4 - (3 - nitrophenyl… 
Highly Cited
1978
Highly Cited
1978
Inhibition of dimethyl sulfoxide-stimulated Friend cell erythrodifferentiation by hydrocortisone and other steroids.
Erythrodifferentiation and hemoglobin synthesis in dimethyl sulfoxide-stimulated Friend erythroleukemia cells were inhibited by… 
1978
1978
Use of resistant or hypersensitive variant clones of Friend cells in analysis of mode of action of inducers.
Abstract Twenty-one variant clones of Friend erythroleukemia cell were isolated and characterized. Seventeen clones were… 
Highly Cited
1974
Highly Cited
1974
Hypoxic cell radiosensitizers: comparative tests of some electron affinic compounds using epidermal cell survival in vivo.
The ability of certain electron affinic compounds to sensitize hypoxic cells to radiation has been tested using an in vivo assay… 
1971
1971
Proliferative kinetics of human hematopoietic cells during different growth phases in vitro.
Summary The proliferation kinetics of an established human hematopoietic cell line (SK-L7) derived from the peripheral blood… 
Highly Cited
1969
Highly Cited
1969
Preliminary clinical trial and the physiologic disposition of 4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide in man.
4(5)-(3,3-Dimethyl-1-triazeno) imidazole-5(4)-carboxamide (DIC, NSC 45388) was administered i.v. to 15 patients with malignant… 
Highly Cited
1968
Highly Cited
1968
Pharmacologic studies of the antitumor agent 5-(dimethyltriazeno)imidazole-4-carboxamide.
Summary In the dog, after an intravenous injection of 5-(dimethyltriazeno)imidazole-4-carboxamide (DIC) at 20 mg/kg (400 mg/sq m… 
1966
1966
N-Amidino-3,5-diamino-6-chloropyrazine-carboxamide : an Active Diuretic in the Carboxamide Series
SINCE the initial observation that steroidal hormones from the adrenal cortex promote renal conservation of sodium was made some… 
1965
1965
The effects of nitrogen mustard and dimethyl myleran on murine leukemia cell lines of different radiosensitivity in vitro.
Summary The effects of nitrogen mustard and dimethyl myleran on 3 mutants of murine leukemia L5178Y—“radioresistant” and…