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Dacarbazine

Known as: Dakarbazin, Dacarbazinum, Dacarbazine - DTIC 
A drug that is used to treat Hodgkin lymphoma and malignant melanoma and is being studied in the treatment of other types of cancer. It attaches to… 
National Institutes of Health

Related topics

Related topics

40 relations

Broader (1)

Antineoplastic Agents, Alkylating

Narrower (12)

BELD protocolBiocarbazineDAV protocolDECAV protocol
Blood Coagulation DisordersCOPDAC RegimenCYVADIC protocolCyVADIC Regimen

Papers overview

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Highly Cited
1994
Highly Cited
1994
Toxicity of uraemia--does it come of AGE?
In the course of normal ageing, and more markedly during hyperglycaemia, proteins are covalently modified and cross-linked… 
1985
1985
1H NMR study of labile proton exchange in the heme cavity as a probe for the potential ligand entry channel in myoglobin.
The exchange rates of heme cavity histidine nitrogen-bound protons in horse and dog metcyanomyoglobins have been determined at 40… 
1983
1983
Erythroleukemia cells: variants inducible for hemoglobin synthesis without commitment to terminal cell division.
Murine erythroleukemia cells (MELC) are virus-transformed erythroid precursors that appear to be blocked at an erythroid… 
Highly Cited
1982
Highly Cited
1982
Binding of a calcium antagonist, [3H]nitrendipine, to high affinity sites in bovine aortic smooth muscle and canine cardiac membranes.
[(3)H]Nitrendipine, a potent calcium channel antagonist [3-ethyl-5-methyl-1-1,4-dihydro-2,6 - dimethyl - 4 - (3 - nitrophenyl… 
Highly Cited
1981
Highly Cited
1981
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives.
The enzyme thromboxane (TX) synthetase is inhibited by pyridine. The beta-substituted pyridine derivatives showed higher… 
Highly Cited
1979
Highly Cited
1979
Use of t-butyldimethylchlorosilane/imidazole reagent for identification of molecular species of phospholipids by gas-liquid chromatography mass spectrometry.
The t-butyldimethylsilyl derivatives of 1,2-diakyl, 1-alk-1'-enyl-2-acyl, 1-alkyl-2-acyl and 1,2-diacyl glycerols were analysed… 
Highly Cited
1978
Highly Cited
1978
Inhibition of dimethyl sulfoxide-stimulated Friend cell erythrodifferentiation by hydrocortisone and other steroids.
Erythrodifferentiation and hemoglobin synthesis in dimethyl sulfoxide-stimulated Friend erythroleukemia cells were inhibited by… 
Highly Cited
1974
Highly Cited
1974
Hypoxic cell radiosensitizers: comparative tests of some electron affinic compounds using epidermal cell survival in vivo.
The ability of certain electron affinic compounds to sensitize hypoxic cells to radiation has been tested using an in vivo assay… 
Highly Cited
1969
Highly Cited
1969
Preliminary clinical trial and the physiologic disposition of 4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide in man.
4(5)-(3,3-Dimethyl-1-triazeno) imidazole-5(4)-carboxamide (DIC, NSC 45388) was administered i.v. to 15 patients with malignant… 
Highly Cited
1968
Highly Cited
1968
Pharmacologic studies of the antitumor agent 5-(dimethyltriazeno)imidazole-4-carboxamide.
Summary In the dog, after an intravenous injection of 5-(dimethyltriazeno)imidazole-4-carboxamide (DIC) at 20 mg/kg (400 mg/sq m…