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Dacarbazine

Known as: Dakarbazin, Dacarbazinum, Dacarbazine - DTIC 
A drug that is used to treat Hodgkin lymphoma and malignant melanoma and is being studied in the treatment of other types of cancer. It attaches to… Expand
National Institutes of Health

Related topics

Related topics

40 relations

Broader (1)

Antineoplastic Agents, Alkylating

Narrower (11)

BELD protocolBiocarbazineDAV protocolDECAV protocol
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Blood Coagulation DisordersCOPDAC RegimenCYVADIC protocolCyVADIC Regimen
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Nivolumab for Newly Diagnosed Advanced-Stage Classic Hodgkin Lymphoma: Safety and Efficacy in the Phase II CheckMate 205 Study.
PURPOSE Nivolumab, an anti-programmed death-1 monoclonal antibody, has demonstrated frequent and durable responses in relapsed… Expand
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Highly Cited
2015
Highly Cited
2015
Nivolumab in previously untreated melanoma without BRAF mutation.
BACKGROUND Nivolumab was associated with higher rates of objective response than chemotherapy in a phase 3 study involving… Expand
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Highly Cited
2011
Highly Cited
2011
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma.
BACKGROUND Ipilimumab monotherapy (at a dose of 3 mg per kilogram of body weight), as compared with glycoprotein 100, improved… Expand
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Highly Cited
2006
Highly Cited
2006
Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group.
PURPOSE Chemotherapy resistance in melanoma has been linked to antiapoptotic effects mediated by Bcl-2 protein. We evaluated… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
CO(2) capture by a task-specific ionic liquid.
Reaction of 1-butyl imidazole with 3-bromopropylamine hydrobromide, followed by workup and anion exchange, yields a new room… Expand
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Highly Cited
2000
Highly Cited
2000
Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma.
PURPOSE To compare, in 305 patients with advanced metastatic melanoma, temozolomide and dacarbazine (DTIC) in terms of overall… Expand
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Highly Cited
1999
Highly Cited
1999
Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma.
PURPOSE Several single-institution phase II trials have reported that the Dartmouth regimen (dacarbazine, cisplatin, carmustine… Expand
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Highly Cited
1994
Highly Cited
1994
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
Production of interleukin-1 and tumour necrosis factor from stimulated human monocytes is inhibited by a new series of pyridinyl… Expand
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Highly Cited
1986
Highly Cited
1986
Characterization of ameboid microglia isolated from developing mammalian brain
Ameboid microglia are isolated from the cerebral tissue of neonatal rat by selective cell adhesion to plastic. Histochemical… Expand
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Highly Cited
1978
Highly Cited
1978
Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.
A human leukemic cell line (designated HL-60) has recently been established from the peripheral blood leukocytes of a patient… Expand
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