Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

PTEN wt Allele

Known as: PTEN1, Phosphatase and Tensin Homolog, MHAM 
Human PTEN wild type allele is located in the vicinity of 10q23.3 and is approximately 109 kb in length. This allele, which encodes… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
  • P. Whiting
  • Current opinion in pharmacology
  • 2006
  • Corpus ID: 39422176
Benzodiazepine (BZ) anxiolytics mediate their clinical effects by enhancing the effect of gamma-aminobutyric acid (GABA) at the… 
  • figure 1
  • figure 2
Review
2005
Review
2005
  • J. Atack
  • Expert opinion on investigational drugs
  • 2005
  • Corpus ID: 22793644
Non-selective benzodiazepine (BZ) binding-site full agonists, exemplified by diazepam, act by enhancing the inhibitory effects of… 
Review
2000
Review
2000
Abstract In his celebrated monolog, the Shakespearean hero Hamlet clearly identified two extreme remedies: "To die: to sleep; no… 
  • figure 1
Highly Cited
2000
Highly Cited
2000
Inhibitory neurotransmission in the brain is largely mediated by GABAA receptors. Potentiation of GABA receptor activation… 
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Review
2000
Review
2000
Both inactivation of the tumor suppressor gene, PTEN/MMAC1, and oncogenic activation of RAS have been described in human… 
  • figure 2
  • figure 1
  • table 1
  • figure 3
Review
1999
Review
1999
PTEN/MMAC1 (phosphatase, tensin homologue/mutated in multiple advanced cancers) is a tumor suppressor protein that has sequence… 
  • figure 1
  • table 1
  • figure 2
  • table 2
  • table 3
Highly Cited
1998
Highly Cited
1998
Deletion of the q23-24 region of human chromosome 10 is one of the most frequent genetic alterations in prostate cancer… 
  • figure 1
  • figure 2
Highly Cited
1997
Highly Cited
1997
A candidate tumor suppressor gene, MMAC1/PTEN, located in human chromosome band 10q23, was recently identified based on sequence… 
  • table 1
  • table 2
  • figure 1
  • figure 2
Highly Cited
1997
Highly Cited
1997
Highly Cited
1978
Highly Cited
1978
  • D. Gallager
  • European journal of pharmacology
  • 1978
  • Corpus ID: 35131783
Based on evidence that the dorsal raphe nucleus (DR) has specific and independent receptors for 5HT, GABA and glycine (Gallager…