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  • Influence
Encoding of Marginal Utility across Time in the Human Brain
TLDR
The data show that anterior cingulate activity correlates with the degree of difficulty associated with dissonance between value and time, and support an integrative architecture for decision making, revealing the neural representation of distinct subcomponents of value that may contribute to impulsivity and decisiveness. Expand
Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review.
TLDR
To inform the political discourse with scientific evidence, the literature was reviewed to identify what is known and not known about the effects of cannabis use on human behavior, including cognition, motivation, and psychosis. Expand
Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study
TLDR
The antagonistic effects of cannabidiol at the CB1 receptor are probably responsible for its profile in smoked cannabis, attenuating the memory-impairing effects of THC. Expand
Mood and cognitive effects of +/-3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy'): week-end 'high' followed by mid-week low.
TLDR
Weekend use of MDMA may lead to depressed mood mid-week, and possible mechanisms underlying the findings are discussed in terms of temporary depletion of serotonin, serotonergic neurotoxity and psychological aspects of mood change. Expand
Can recreational doses of THC produce significant dopamine release in the human striatum?
TLDR
It is shown that recreational cannabis users do not release significant amounts of dopamine from an oral THC dose equivalent to a standard cannabis cigarette, which challenges current models of striatal dopamine release as the mechanism mediating cannabis as risk factor for schizophrenia. Expand
Acute Effects of Ketamine on Memory Systems and Psychotic Symptoms in Healthy Volunteers
TLDR
The data suggest that, in humans, ketamine produces a selective pattern of impairments to working, episodic, and procedural memory but not to perceptual priming, attention or aspects of executive functioning. Expand
Keep off the grass? Cannabis, cognition and addiction
TLDR
The current state of knowledge about vulnerability factors, the variations in types of cannabis, and the relationship between these and cognition and addiction are reviewed. Expand
Cognitive and subjective effects of mephedrone and factors influencing use of a 'new legal high'.
TLDR
Mephedrone impairs working memory acutely, induces stimulant-like effects in users and is associated with binge use, which might help to predict future trends in use of the many new psychoactive substances emerging on the internet. Expand
Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis
TLDR
Hair samples were analysed to examine levels of Δ9-THC and CBD in 140 individuals and three clear groups emerged: ’THC only’, ‘THC+CBD’ and those with no cannabinoid in hair, which provides evidence of the divergent properties of cannabinoids. Expand
Acute and chronic effects of ketamine upon human memory: a review
TLDR
This article reviews the existing literature on the effects of acute ketamine on the memory of healthy volunteers and of repeated doses of ketamine in recreational users and suggests that ketamine may differ from other classic amnestic drugs in impairing aspects of semantic memory. Expand
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