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Encoding of Marginal Utility across Time in the Human Brain
The data show that anterior cingulate activity correlates with the degree of difficulty associated with dissonance between value and time, and support an integrative architecture for decision making, revealing the neural representation of distinct subcomponents of value that may contribute to impulsivity and decisiveness.
Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review.
To inform the political discourse with scientific evidence, the literature was reviewed to identify what is known and not known about the effects of cannabis use on human behavior, including cognition, motivation, and psychosis.
Mood and cognitive effects of +/-3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy'): week-end 'high' followed by mid-week low.
Weekend use of MDMA may lead to depressed mood mid-week, and possible mechanisms underlying the findings are discussed in terms of temporary depletion of serotonin, serotonergic neurotoxity and psychological aspects of mood change.
Acute Effects of Ketamine on Memory Systems and Psychotic Symptoms in Healthy Volunteers
- C. Morgan, Ali Mofeez, B. Brandner, L. Bromley, H. Curran
- Psychology, BiologyNeuropsychopharmacology
The data suggest that, in humans, ketamine produces a selective pattern of impairments to working, episodic, and procedural memory but not to perceptual priming, attention or aspects of executive functioning.
Can recreational doses of THC produce significant dopamine release in the human striatum?
Keep off the grass? Cannabis, cognition and addiction
- H. Curran, T. Freeman, C. Mokrysz, David A. Lewis, C. Morgan, L. Parsons
- MedicineNature Reviews Neuroscience
- 1 May 2016
The current state of knowledge about vulnerability factors, the variations in types of cannabis, and the relationship between these and cognition and addiction are reviewed.
Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study
- C. Morgan, G. Schafer, T. Freeman, H. Curran
- Medicine, PsychologyBritish Journal of Psychiatry
- 1 October 2010
The antagonistic effects of cannabidiol at the CB1 receptor are probably responsible for its profile in smoked cannabis, attenuating the memory-impairing effects of THC.
Consequences of chronic ketamine self-administration upon neurocognitive function and psychological wellbeing: a 1-year longitudinal study.
Findings imply that heavy use of ketamine is harmful to aspects of both cognitive function and psychological wellbeing.
Acute and chronic effects of ketamine upon human memory: a review
This article reviews the existing literature on the effects of acute ketamine on the memory of healthy volunteers and of repeated doses of ketamine in recreational users and suggests that ketamine may differ from other classic amnestic drugs in impairing aspects of semantic memory.
Cognitive and subjective effects of mephedrone and factors influencing use of a 'new legal high'.
- T. Freeman, C. Morgan, James Vaughn-Jones, Nahida Hussain, K. Karimi, H. Curran
- Psychology, MedicineAddiction
- 1 April 2012
Mephedrone impairs working memory acutely, induces stimulant-like effects in users and is associated with binge use, which might help to predict future trends in use of the many new psychoactive substances emerging on the internet.