Skip to search formSkip to main contentSkip to account menu

PRPF8 gene

Known as: Prp8, hPrp8, SNRNP220 
National Institutes of Health

Related topics

Related topics

1 relation
PRPF8 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Dynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes
Little is known about contacts in the spliceosome between proteins and intron nucleotides surrounding the pre-mRNA branch-site… 
2004
2004
Identification of Toposome, A Novel Multisubunit Complex Containing Topoisomerase II-alpha
Topoisomerase ??-alpha plays essential roles in chromosome segregation. However, it is not well understood how topoisomerase II… 
2002
2002
Clinical characterization, linkage analysis, and PRPC8 mutation analysis of a family with autosomal dominant retinitis pigmentosa type 13 (RP13)
A Dutch family with autosomal dominant retinitis pigmentosa (adRP) displayed a phenotype characterized by an early age of onset… 
2001
2001
A nuclear‐encoded intein in the fungal pathogen Cryptococcus neoformans
We have used comparative sequence analysis to identify an intein‐like sequence (protein splicing element) present in Cryptococcus… 
1999
1999
Trichomonas vaginalis possesses a gene encoding the essential spliceosomal component, PRP8.
Highly Cited
1995
Highly Cited
1995
Interaction of the yeast splicing factor PRP8 with substrate RNA during both steps of splicing.
PRP8 protein of Saccharomyces cerevisiae interacts directly with pre-mRNA in spliceosomes, shown previously by UV-crosslinking… 
Review
1995
Review
1995
The role of PRP8 protein in nuclear pre-mRNA splicing in yeast
SUMMARY The removal of introns from precursor messenger RNAs occurs in a large complex, the spliceosome, that contains many… 
1991
1991
The yeast PRP8 protein interacts directly with pre-mRNA.
The PRP8 protein of Saccharomyces cerevisiae is required for nuclear pre-mRNA splicing. Previously, immunological procedures… 
1990
1990
A mammalian protein of 220 kDa binds pre-mRNAs in the spliceosome: a potential homologue of the yeast PRP8 protein.
A mammalian protein of approximately 220 kDa (p220) was UV-crosslinked to precursor mRNAs (pre-mRNAs) under splicing conditions… 
Highly Cited
1989
Highly Cited
1989
The mammalian analogue of the yeast PRP8 splicing protein is present in the U4/5/6 small nuclear ribonucleoprotein particle and the spliceosome.
HeLa cell nuclear extracts contain a protein reactive with antibodies against PRP8, a polypeptide essential for pre-mRNA splicing… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)