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PRF1 wt Allele

Known as: MGC65093, PFN1, Perforin 1 (Pore Forming Protein) wt Allele 
Human PRF1 wild-type allele is located in the vicinity of 10q22 and is approximately 5 kb in length. This allele, which encodes perforin-1 protein… Expand
National Institutes of Health

Papers overview

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2020
2020
Paget's disease of bone (PDB) is a late‐onset disorder frequently caused by mutations in the SQSTM1 gene, leading to hyperactive… Expand
2019
2019
The large magnitude of protein-protein interaction (PPI) pairs within the human interactome necessitates the development of… Expand
2018
2018
The large magnitude of protein-protein interaction (PPI) pairs within the human interactome necessitates the development of… Expand
2014
2014
Evidence of genetic heterogeneity in ALS has been found, with at least 31 genes being identified to date as causing ALS, and… Expand
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2014
2014
But de la presentation Le score SMILE (Scaled Measurement of Improvement in Lip Excursion) est un score valide (Bray et al., 2010… Expand
2013
2013
UBQLN2 and PFN1 were recently associated with amyotrophic lateral sclerosis (ALS). We investigated a role for these ALS genes in… Expand
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2013
2013
Mutations in PFN1, a gene encoding the actin monomer-binding protein profilin 1, were recently reported in 1% to 2% of familial… Expand
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2012
2012
Profilins are prominent regulators of actin dynamics. While most mammalian cells express only one profilin, two isoforms, PFN1… Expand
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Highly Cited
2010
Highly Cited
2010
Two profilin isoforms (PFN1 and PFN2a) are expressed in the mammalian brain. Although profilins are essential for regulating… Expand
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Review
1996
Review
1996
Between 1 December 1994 and 31 January 1995, Salmonella agona infections increased abruptly in England and Wales; isolates of S… Expand