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PRF1 gene

Known as: P1, perforin 1 (preforming protein), PERFORIN 1 
This gene is involved in cytolysis.
National Institutes of Health

Related topics

Related topics

12 relations
Antitumor ResponseAntiviral ResponseApoptosisCell-Mediated Cytolysis

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PRF1 wt Allele

Papers overview

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2012
2012
First autologous hematopoietic SCT for ankylosing spondylitis: a case report and clues to understanding the therapy
First autologous hematopoietic SCT for ankylosing spondylitis: a case report and clues to understanding the therapy 
2008
2008
CD8+ T Cells Targeting a Single Immunodominant Epitope are Sufficient for Elimination of Established SV40 T Antigen-Induced Brain Tumors1
Immunotherapy of established solid tumors is rarely achieved, and the mechanisms leading to success remain to be elucidated. We… 
2008
2008
Establishment and Characterization of a Cell Based Artificial Antigen-Presenting Cell for Expansion and Activation of CD8+ T Cells Ex Vivo
Artificial antigen-presenting cells are expected to stimulate the expansion and acquisition of optimal therapeutic features of T… 
2004
2004
Lymphocytic gastritis in pediatric celiac disease -- immunohistochemical study of the intraepithelial lymphocytic component.
BACKGROUND Lymphocytic gastritis (LG) is defined by the recognition of >25 intraepithelial lymphocytes (IEL) per 100 surface… 
2003
2003
Natural killer cells in the synovial fluid of rheumatoid arthritis patients exhibit a CD 56 bright , CD 94 bright , CD 158 negative phenotype
Background. Natural killer (NK) cells play an important role in several animal models of autoimmunity by modulating T-cell… 
1999
1999
IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor
1998
1998
Perforin and IFN-gamma are involved in the antitumor effects of antibody-targeted superantigens.
The bacterial superantigen staphylococcal enterotoxin A (SEA) is a potent inducer of cytokine production and cytotoxic T cell… 
1990
1990
Homology of perforin to the ninth component of complement (C9)
1989
1989
Molecular cloning of rat cytolysin.
Rat cytolysin is one of the cytolytic factors present in the cytoplasmic granules of rat NK-like cytolytic cells and purified… 
1987
1987
Cellular localization of perforin 1 in murine cloned cytotoxic T lymphocytes.
The localization of perforin 1 (P1) in cytotoxic cells was studied by immuno-electron microscopy by using a monospecific rabbit… 
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