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10q22

A chromosome band present on 10q
National Institutes of Health

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4 relations
10qChromosomesPRF1 wt AlleleVDAC2 wt Allele

Papers overview

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Highly Cited
2012
Highly Cited
2012
Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci.
Psoriasis (PS) and Crohn disease (CD) have been shown to be epidemiologically, pathologically, and therapeutically connected, but… Expand
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Highly Cited
2009
Highly Cited
2009
Common variants at five new loci associated with early-onset inflammatory bowel disease
The inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis are common causes of morbidity in children and young… Expand
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Highly Cited
2005
Highly Cited
2005
Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family
Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Epigenetic inheritance is involved in… Expand
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Highly Cited
2005
Highly Cited
2005
Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder
The large conductance calcium-sensitive potassium (BK) channel is widely expressed in many organs and tissues, but its in vivo… Expand
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Highly Cited
2004
Highly Cited
2004
The parent-of-origin effect of 10q22 in pre-eclamptic females coincides with two regions clustered for genes with down-regulated expression in androgenetic placentas.
By affected sib-pair linkage analysis of 24 families with pre-eclampsia, we confirm a susceptibility locus on chromosome 10q22.1… Expand
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Highly Cited
2003
Highly Cited
2003
Genomewide linkage scan for schizophrenia susceptibility loci among Ashkenazi Jewish families shows evidence of linkage on chromosome 10q22.
Previous linkage studies in schizophrenia have been discouraging due to inconsistent findings and weak signals. Genetic… Expand
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Review
2000
Review
2000
PTEN, a unique tumor suppressor gene.
For many years, it has been thought that the chromosome region 10q22-24 includes one or more genes that appear to play a role in… Expand
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Highly Cited
1999
Highly Cited
1999
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast.
Germline mutations in PTEN, encoding a dual-specificity phosphatase on 10q23.3, cause Cowden syndrome (CS), which is… Expand
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Highly Cited
1997
Highly Cited
1997
Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease.
Cowden disease, also known as multiple hamartoma syndrome, is an autosomal dominant cancer syndrome with a high risk of breast… Expand
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Highly Cited
1994
Highly Cited
1994
Loss of heterozygosity for 10q22-10qter in malignant melanoma progression.
Karyotypic and molecular data indicate that genetic events involving the chromosome region 10q22-10qter may be related to… Expand
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