PMAIP1 wt Allele

Known as: APR, NOXA, Phorbol-12-Myristate-13-Acetate-Induced Protein 1 wt Allele 
Human PMAIP1 wild-type allele is located in the vicinity of 18q21.32 and is approximately 4 kb in length. This allele, which encodes phorbol-12… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
DNA-damaging chemotherapy is the backbone of cancer treatment, although it is not clear how such treatments kill tumor cells. In… (More)
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2009
2009
BACKGROUND & AIMS Hepatocyte apoptosis is a key event in non-alcoholic steatohepatitis (NASH). We studied the effect of obesity… (More)
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Highly Cited
2007
Highly Cited
2007
The gradual accumulation of chronic lymphocytic leukemia (B-CLL) cells is presumed to derive from proliferation centers in lymph… (More)
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2007
2007
Defects in the apoptotic machinery may contribute to chemoresistance of non-small cell lung cancer (NSCLC) cells. We have… (More)
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Highly Cited
2006
Highly Cited
2006
Cisplatin is one of the most common DNA-damaging agents used for treating patients with solid tumors such as squamous cell… (More)
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Highly Cited
2005
Highly Cited
2005
Numerous p53 target genes have been implicated in DNA damage-induced apoptosis signaling, but proapoptotic Bcl-2 (B-cell leukemia… (More)
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Highly Cited
2003
Highly Cited
2003
The transcription factor c-Jun mediates several cellular processes, including proliferation and survival, and is upregulated in… (More)
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Highly Cited
2003
Highly Cited
2003
Apoptosis provoked by DNA damage requires the p53 tumor suppressor, but which of the many p53-regulated genes are required has… (More)
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Highly Cited
2003
Highly Cited
2003
NADPH oxidases (Nox) have been characterized as higher eukaryotic enzymes used deliberately to produce reactive oxygen species… (More)
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Review
2001
Review
2001
Liver fibrosis represents the uniform response of liver to toxic, infectious or metabolic agents. The process leading to liver… (More)
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