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PMAIP1 wt Allele

Known as: APR, NOXA, Phorbol-12-Myristate-13-Acetate-Induced Protein 1 wt Allele 
Human PMAIP1 wild-type allele is located in the vicinity of 18q21.32 and is approximately 4 kb in length. This allele, which encodes phorbol-12… Expand
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Trp63, a transcription factor related to the tumor suppressor p53, is activated by diverse stimuli and can initiate a range of… Expand
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Highly Cited
2009
Highly Cited
2009
Evasion of apoptosis contributes importantly to c-Myc-induced tumorigenesis. The BH3-only Bcl-2 family members Puma and Noxa are… Expand
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Highly Cited
2007
Highly Cited
2007
The gradual accumulation of chronic lymphocytic leukemia (B-CLL) cells is presumed to derive from proliferation centers in lymph… Expand
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Highly Cited
2006
Highly Cited
2006
Cisplatin is one of the most common DNA-damaging agents used for treating patients with solid tumors such as squamous cell… Expand
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Highly Cited
2005
Highly Cited
2005
Numerous p53 target genes have been implicated in DNA damage-induced apoptosis signaling, but proapoptotic Bcl-2 (B-cell leukemia… Expand
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Highly Cited
2003
Highly Cited
2003
Apoptosis provoked by DNA damage requires the p53 tumor suppressor, but which of the many p53-regulated genes are required has… Expand
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Highly Cited
2003
Highly Cited
2003
The transcription factor c-Jun mediates several cellular processes, including proliferation and survival, and is upregulated in… Expand
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Highly Cited
2003
Highly Cited
2003
NADPH oxidases (Nox) have been characterized as higher eukaryotic enzymes used deliberately to produce reactive oxygen species… Expand
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Highly Cited
2002
Highly Cited
2002
The in vivo response to radiotherapy is not well understood but appears to involve the p53 tumor suppressor protein. We… Expand
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Review
2001
Review
2001
Liver fibrosis represents the uniform response of liver to toxic, infectious or metabolic agents. The process leading to liver… Expand
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