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Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry.
- A. J. Maniotis, R. Folberg, +6 authors M. Hendrix
- Biology, Medicine
- The American journal of pathology
- 1 September 1999
Tissue sections from aggressive human intraocular (uveal) and metastatic cutaneous melanomas generally lack evidence of significant necrosis and contain patterned networks of interconnected loops of… Expand
The transcriptional program in the response of human fibroblasts to serum.
The temporal program of gene expression during a model physiological response of human cells, the response of fibroblasts to serum, was explored with a complementary DNA microarray representing about… Expand
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer.
Members of the recently recognized SRC-1 family of transcriptional coactivators interact with steroid hormone receptors to enhance ligand-dependent transcription. AIB1, a member of the SRC-1 family,… Expand
KiSS-1, a novel human malignant melanoma metastasis-suppressor gene.
- J. Lee, M. E. Miele, +4 authors D. Welch
- Medicine, Biology
- Journal of the National Cancer Institute
- 4 December 1996
BACKGROUND Microcell-mediated transfer of chromosome 6 into human C8161 and MelJuSo melanoma cell suppresses their ability to metastasize by at least 95% without affecting their tumorigenicity. This… Expand
High frequency of BRAF mutations in nevi
To evaluate the timing of mutations in BRAF (v-raf murine sarcoma viral oncogene homolog B1) during melanocytic neoplasia, we carried out mutation analysis on microdissected melanoma and nevi… Expand
Use of a cDNA microarray to analyse gene expression patterns in human cancer
The development and progression of cancer1–3 and the experimental reversal of tumorigenicity4,5 are accompanied by complex changes in patterns of gene expression. Microarrays of cDNA provide a… Expand
HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome
We report here the identification of a gene associated with the hyperparathyroidism–jaw tumor (HPT–JT) syndrome. A single locus associated with HPT–JT (HRPT2) was previously mapped to chromosomal… Expand
Genomic Classification of Cutaneous Melanoma
We describe the landscape of genomic alterations in cutaneous melanomas through DNA, RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 patients. We establish a… Expand
Comparative properties of five human ovarian adenocarcinoma cell lines.
We describe the derivation of three human ovarian carcinoma cell lines and the comparison of their properties with two previously described cell lines of like histology (SKOV-3 and CAOV-3). Two of… Expand
Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search
Despite its high prevalence, very little is known regarding genetic predisposition to prostate cancer. A genome-wide scan performed in 66 high-risk prostate cancer families has provided evidence of… Expand