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PMAIP1 gene

Known as: APR, NOXA, Phorbol-12-Myristate-13-Acetate-Induced Protein 1 Gene 
This gene is a regulator of apoptosis through transcriptional activation.
National Institutes of Health

Related topics

Related topics

4 relations
ApoptosisPositive Regulation of Apoptosisphorbol-12-myristate-13-acetate-induced protein 1

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PMAIP1 wt Allele

Papers overview

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2016
2016
The Evaluation and Comparison of Transcriptionally Targeted Noxa and Puma Killer Genes to Initiate Apoptosis Under Cancer-Specific Promoter CXCR1 in Hepatocarcinoma Gene Therapy
Background Cancerous cells proliferate as fast as possible without a proper surveillance system. This rapid cell division leads… 
2016
2016
Generation of Reactive Oxygen Species via NOXa Is Important for Development and Pathogenicity of Mycosphaerella graminicola
Abstract The ascomycete fungus Mycosphaerella graminicola (synonym Zymoseptoria tritici) is an important pathogen of wheat… 
2015
2015
An Integrative Analysis of the Putative Gefitinib-resistance Related Genes in a Lung Cancer Cell Line Model System.
The epidermal growth factor receptor-tyrosine kinase inhibitors (EGFRTKI), such as gefitinib and erlotinib have improved the… 
2013
2013
Toward personalized therapy for chronic lymphocytic leukemia
The differences in clinical course of chronic lymphocytic leukemia could have an impact on variations in a patient’s response to… 
2012
2012
Artificial Neural Network based dynamic modelling of indigenous pneumatic muscle actuators
  • P. JamwalS. Xie
  • Proceedings of IEEE/ASME 8th IEEE/ASME…
  • 2012
  • Corpus ID: 18573138
Robots are increasingly becoming popular medical devices, helping surgeons and practitioners as surgical, rehabilitation or… 
2010
2010
Essential role of PI3-kinase pathway in p53-mediated transcription: Implications in cancer chemotherapy
The PI3-kinase pathway is the target of inactivation in achieving better cancer chemotherapy. Here, we report that p53-mediated… 
2008
2008
Identification and characterization of two splicing variants of human Noxa.
Noxa is a pro-apoptotic Bcl-2 homology 3 (BH3)-only containing protein. Here we report the identification of two splicing… 
2008
2008
Altered Expression of the PMAIP1 Gene: A Major Player in the Evolution of Gastrointestinal and Systemic Malignancies
To the Editor I read with interest the recent article by Ishida et al. [1] in a recent issue of this journal. The PMAIP1 gene is… 
2005
2005
Involvement of Bcl-2 family proteins in p53-induced apoptosis.
  • K. Tobiume
  • Journal of Nippon Medical School = Nippon Ika…
  • 2005
  • Corpus ID: 9815907
Mutations in the p53 tumor suppressor gene occur in more than 50% of human cancers. In response to various cellular stresses… 
2003
2003
Noxa in colorectal cancer: a study on DNA, mRNA and protein expression
Noxa is a BH3-only member of the Bcl-2 family, upregulated by p53 as a response to DNA damage. Mutations in the BH3-only region… 
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