phorbol-12-myristate-13-acetate-induced protein 1

Known as: Protein Noxa, NOXA, PMA-Induced Protein 1 
Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (54 aa, ~6 kDa) is encoded by the human PMAIP1 gene. This protein plays a role in the activation of… (More)
National Institutes of Health

Papers overview

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2011
2011
The objective was to investigate the upstream apoptotic mechanisms that were triggered by a styrylpyrone derivative… (More)
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Review
2007
Review
2007
Impaired apoptosis is both critical in cancer development and a major barrier to effective treatment. In response to diverse… (More)
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Review
2006
Review
2006
Following the induction of DNA damage, a prominent route of cell inactivation is apoptosis. During the last ten years, specific… (More)
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Highly Cited
2006
Highly Cited
2006
Although the BCL-2 family constitutes a crucial checkpoint in apoptosis, the intricate interplay between these family members… (More)
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Highly Cited
2005
Highly Cited
2005
Commitment of cells to apoptosis is governed largely by the interaction between members of the Bcl-2 protein family. Its three… (More)
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Highly Cited
2005
Highly Cited
2005
Apoptosis is initiated when Bcl-2 and its prosurvival relatives are engaged by proapoptotic BH3-only proteins via interaction of… (More)
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Review
2005
Review
2005
BH3-only members of the Bcl-2 intracellular protein family, which include Bim, Bmf, Bik, Bad, Bid, Puma, Noxa and Hrk, mediate… (More)
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Highly Cited
2003
Highly Cited
2003
Apoptosis provoked by DNA damage requires the p53 tumor suppressor, but which of the many p53-regulated genes are required has… (More)
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Highly Cited
2001
Highly Cited
2001
Critical issues in apoptosis include the importance of caspases versus organelle dysfunction, dominance of anti- versus… (More)
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Highly Cited
2000
Highly Cited
2000
A critical function of tumor suppressor p53 is the induction of apoptosis in cells exposed to noxious stresses. We report a… (More)
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