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PLP1 gene

Known as: Proteolipid Protein 1 (Pelizaeus-Merzbacher Disease, Spastic Paraplegia 2, Uncomplicated) Gene, DM20, PROTEOLIPID PROTEIN, MYELIN 
This gene is involved in neuronal development.
National Institutes of Health

Related topics

Related topics

4 relations
Myelin Proteolipid ProteinNeurogenesisPLP1 protein, humanPelizaeus-Merzbacher Disease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Evidence for a second wave of oligodendrogenesis in the postnatal cerebral cortex of the mouse
The existing view is that cortical oligodendrocytes (OLs) in rodents are born from the cortical subventricular zone (SVZ) after… 
Highly Cited
2001
Highly Cited
2001
Myelin proteolipid proteins promote the interaction of oligodendrocytes and axons
Although proteolipid protein (PLP) and its DM20 isoform are the major membrane proteins of CNS myelin, their absence causes… 
Highly Cited
1999
Highly Cited
1999
Identification of a New Exon in the Myelin Proteolipid Protein Gene Encoding Novel Protein Isoforms That Are Restricted to the Somata of Oligodendrocytes and Neurons
The myelin proteolipid protein (PLP) gene (i.e., the PLP/DM20 gene) has been of some interest because of its role in certain… 
1997
1997
Nonsense mutation in exon 3 of the proteolipid protein gene (PLP) in a family with an unusual form of Pelizaeus-Merzbacher disease.
We report a G-->A transition at nucleotide 431 of the proteolipid protein gene (PLP) results in a nonsense codon in a family with… 
1997
1997
Proteolipid Protein Regulates the Survival and Differentiation of Oligodendrocytes
Proteolipid protein (PLP) has been postulated to play a critical role in the early differentiation of oligodendrocytes (OLs) in… 
Highly Cited
1994
Highly Cited
1994
Intracellular transport and sorting of the oligodendrocyte transmembrane proteolipid protein
Delineating the properties and functions of the major central nervous system myelin proteins has been the focus of intensive… 
Highly Cited
1994
Highly Cited
1994
Proteolipid protein interactions in transfectants: Implications for myelin assembly
The proteolipid proteins (PLP and DM20) are major constituents of CNS myelin, but how they are delivered to and organized within… 
Highly Cited
1993
Highly Cited
1993
A proteolipid protein gene family: Expression in sharks and rays and possible evolution from an ancestral gene encoding a pore-forming polypeptide
Highly Cited
1991
Highly Cited
1991
Pelizaeus-Merzbacher disease: a valine to phenylalanine point mutation in a putative extracellular loop of myelin proteolipid.
In the central nervous system, myelin proteolipid protein isoforms (PLP and DM20) play an essential structural role in… 
Highly Cited
1977
Highly Cited
1977
Lipid phase separation induced by a hydrophobic protein in phosphatidylserine--phosphatidylcholine vesicles.
Differential scanning calorimetry (DSC) was used to detect phase separation induced by hydrophobic myelin protein, lipophilin, in… 
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