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PLP1 gene

Known as: Proteolipid Protein 1 (Pelizaeus-Merzbacher Disease, Spastic Paraplegia 2, Uncomplicated) Gene, DM20, PROTEOLIPID PROTEIN, MYELIN 
This gene is involved in neuronal development.
National Institutes of Health

Related topics

Related topics

4 relations
Myelin Proteolipid ProteinNeurogenesisPLP1 protein, humanPelizaeus-Merzbacher Disease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Evidence for a second wave of oligodendrogenesis in the postnatal cerebral cortex of the mouse
The existing view is that cortical oligodendrocytes (OLs) in rodents are born from the cortical subventricular zone (SVZ) after… 
2003
2003
Soma-Restricted Products of the Myelin Proteolipid Gene Are Expressed Primarily in Neurons in the Developing Mouse Nervous System
The myelin proteolipid gene encodes two sets of proteins, the classic PLP and DM20 and the sr (soma-restricted)-PLP and sr-DM20… 
2001
2001
Mammaglobin is found in breast tissue as a complex with BU101.
The mammaglobin gene has been shown to be preferentially expressed in breast tissue. Few genes match its specificity. Mammaglobin… 
Highly Cited
2001
Highly Cited
2001
Myelin proteolipid proteins promote the interaction of oligodendrocytes and axons
Although proteolipid protein (PLP) and its DM20 isoform are the major membrane proteins of CNS myelin, their absence causes… 
Highly Cited
1999
Highly Cited
1999
Identification of a New Exon in the Myelin Proteolipid Protein Gene Encoding Novel Protein Isoforms That Are Restricted to the Somata of Oligodendrocytes and Neurons
The myelin proteolipid protein (PLP) gene (i.e., the PLP/DM20 gene) has been of some interest because of its role in certain… 
Highly Cited
1994
Highly Cited
1994
Intracellular transport and sorting of the oligodendrocyte transmembrane proteolipid protein
Delineating the properties and functions of the major central nervous system myelin proteins has been the focus of intensive… 
Highly Cited
1994
Highly Cited
1994
Proteolipid protein interactions in transfectants: Implications for myelin assembly
The proteolipid proteins (PLP and DM20) are major constituents of CNS myelin, but how they are delivered to and organized within… 
Highly Cited
1991
Highly Cited
1991
Pelizaeus-Merzbacher disease: a valine to phenylalanine point mutation in a putative extracellular loop of myelin proteolipid.
In the central nervous system, myelin proteolipid protein isoforms (PLP and DM20) play an essential structural role in… 
1991
1991
Mutations in the Myelin Proteolipid Protein Gene Alter Oligodendrocyte Gene Expression in Jimpy and Jimpymsd Mice
Abstract: The mouse myelin proteolipid protein (PLP) gene has been studied in normal and jimpymsd mice. Potential upstream… 
1986
1986
Lipophilin (PLP) Gene in X‐linked myelin disorders
There are several X‐linked diseases in animals and at least one in man in which there is a failure of CNS myelination. We have… 
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