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PLP1 gene

Known as: Proteolipid Protein 1 (Pelizaeus-Merzbacher Disease, Spastic Paraplegia 2, Uncomplicated) Gene, DM20, PROTEOLIPID PROTEIN, MYELIN 
This gene is involved in neuronal development.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Neural stem cell transplantation study suggests myelin formation in children with a severe hypomyelination disorder. Bringing… Expand
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Highly Cited
2007
Highly Cited
2007
The prevailing mechanism for recurrent and some nonrecurrent rearrangements causing genomic disorders is nonallelic homologous… Expand
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Highly Cited
2007
Highly Cited
2007
Mice lacking the expression of proteolipid protein (PLP)/DM20 in oligodendrocytes provide a genuine model for spastic paraplegia… Expand
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Review
2002
Review
2002
T cells that can respond to self-antigens are present in the peripheral immune repertoire of all healthy individuals. Recently we… Expand
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Highly Cited
2002
Highly Cited
2002
Myelination, the process by which glial cells ensheath and electrically insulate axons, has been investigated intensely… Expand
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Highly Cited
2001
Highly Cited
2001
This study addresses the role of Sonic hedgehog (Shh) in promoting the generation of oligodendrocytes in the mouse telencephalon… Expand
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Highly Cited
2000
Highly Cited
2000
Intrathymic expression of tissue-specific self antigens may be involved in immunological tolerance and protection from autoimmune… Expand
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Highly Cited
1998
Highly Cited
1998
Glial cells produce myelin and contribute to axonal morphology in the nervous system. Two myelin membrane proteolipids, PLP and… Expand
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Highly Cited
1997
Highly Cited
1997
Two proteolipid proteins, PLP and DM20, are the major membrane components of central nervous system (CNS) myelin. Mutations of… Expand
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Highly Cited
1994
Highly Cited
1994
Three forms of X–linked spastic paraplegia (SPG) have been defined. One locus (SPG 1) maps to Xq28 while two clinically distinct… Expand
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