• Publications
  • Influence
Tbr1 Regulates Differentiation of the Preplate and Layer 6
During corticogenesis, early-born neurons of the preplate and layer 6 are important for guiding subsequent neuronal migrations and axonal projections. Tbr1 is a putative transcription factor that isExpand
  • 727
  • 41
  • PDF
Visualization of corticofugal projections during early cortical development in a τ‐GFP‐transgenic mouse
The first postmitotic neurons in the developing neocortex establish the preplate layer. These early‐born neurons have a significant influence on the circuitry of the developing cortex. However, theExpand
  • 105
  • 25
Structure and developmental regulation of Golli-mbp, a 105-kilobase gene that encompasses the myelin basic protein gene and is expressed in cells in the oligodendrocyte lineage in the brain.
We have identified a novel transcription unit of 105 kilobases (called the Golli-mbp gene) that encompasses the mouse myelin basic protein (MBP) gene. Three unique exons within this gene areExpand
  • 228
  • 12
Developmental Regulation of the Distribution of Aromatase- and Estrogen-Receptor- mRNA-Expressing Cells in the Zebra Finch Brain
Strong evidence exists for the masculinizing effects of estrogen on the neural network that controls song learning and behavior in zebra finches. However, the mechanisms by which estrogen acts toExpand
  • 93
  • 10
Expression of Myelin Protein Genes and Other Myelin Components in an Oligodendrocytic Cell Line Conditionally Immortalized with a Temperature‐Sensitive Retrovirus
Abstract: We have conditionally immortalized oligodendrocytes isolated from normal and shiverer primary mouse brain cultures through the use of the retroviral vector ZIPSVtsA58. This vector encodesExpand
  • 108
  • 9
Central nervous system myelination in mice with deficient expression of Notch1 receptor
Activity of the Notch1 gene is known to inhibit oligodendrocyte (OL) differentiation in vitro. We tested the hypothesis that the Notch1 pathway regulates in vivo myelin formation, by examining brainExpand
  • 117
  • 8
  • PDF
Identification of a New Exon in the Myelin Proteolipid Protein Gene Encoding Novel Protein Isoforms That Are Restricted to the Somata of Oligodendrocytes and Neurons
The myelin proteolipid protein (PLP) gene (i.e., the PLP/DM20 gene) has been of some interest because of its role in certain human demyelinating diseases, such as Pelizaeus-Merzbacher disease. AExpand
  • 75
  • 8
  • PDF
Myelin Basic Protein Gene
Publisher Summary The myelin basic proteins (MBPs) and the myelin proteolipid proteins (PLPs) are the major myelin proteins. These proteins account for at least 80% of the protein found in myelin.Expand
  • 35
  • 8
Identification of a cDNA coding for a fifth form of myelin basic protein in mouse.
The primary sequences of four molecular mass variants (14, 17, 18.5, and 21.5 kDa) of the mouse myelin basic protein (MBP) have recently been determined through analysis of cDNA clones of theirExpand
  • 123
  • 7
  • PDF
Golli protein negatively regulates store depletion-induced calcium influx in T cells.
Calcium influx is crucial for T cell activation and differentiation. The detailed regulation of this process remains unclear. We report here that golli protein, an alternatively spliced product ofExpand
  • 74
  • 7