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PKG activity
Known as:
cGMP-dependent protein kinase ibeta activity
, PKG
, 3':5'-cyclic GMP-dependent protein kinase activity
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Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP. [GOC:mah]
National Institutes of Health
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Related topics
Related topics
2 relations
Cyclic GMP-Dependent Protein Kinases
PRKG1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Controlling anoxic tolerance in adult Drosophila via the cGMP–PKG pathway
Ken Dawson-Scully
,
D. Bukvic
,
M. Chakaborty-Chatterjee
,
R. Ferreira
,
Sarah L. Milton
,
Marla B. Sokolowski
Journal of Experimental Biology
2010
Corpus ID: 23747608
SUMMARY In this study we identify a cGMP-dependent protein kinase (PKG) cascade as a biochemical pathway critical for controlling…
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Highly Cited
2007
Highly Cited
2007
Protein kinase G-mediated stimulation of basal Leydig cell steroidogenesis.
S. Andric
,
M. Janjic
,
N. Stojkov
,
T. Kostic
American Journal of Physiology. Endocrinology and…
2007
Corpus ID: 19127835
The androgen-secreting Leydig cells produce cGMP, but the pathways responsible for generation and actions of this intracellular…
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2007
2007
Guanosine 3',5'-cyclic monophosphate (cGMP)/cGMP-dependent protein kinase induce interleukin-6 transcription in osteoblasts.
K. Broderick
,
Tong Zhang
,
+4 authors
R. Pilz
Molecular Endocrinology
2007
Corpus ID: 15231027
Natriuretic peptides and nitric oxide (NO) activate the cGMP/cGMP-dependent protein kinase (PKG) signaling pathway and play an…
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2006
2006
PGI2 opens potassium channels in retinal pericytes by cyclic AMP-stimulated, cross-activation of PKG.
J. Burnette
,
Richard E. White
Experimental Eye Research
2006
Corpus ID: 1872375
2005
2005
Phasic cardiovascular responses to mevinphos are mediated through differential activation of cGMP/PKG cascade and peroxynitrite via nitric oxide generated in the rat rostral ventrolateral medulla by…
JulieY.H. Chan
,
S. H. Chan
,
Faith C. H. Li
,
Ching-Yi Tsai
,
Hsiao-Lei Cheng
,
A. Chang
Neuropharmacology
2005
Corpus ID: 26021251
2003
2003
Inhibition of cyclic guanosine 5'-monophosphate-dependent protein kinase I (PKG-I) in lumbar spinal cord reduces formalin-induced hyperalgesia and PKG upregulation.
A. Schmidtko
,
P. Ruth
,
G. Geisslinger
,
I. Tegeder
Nitric oxide
2003
Corpus ID: 30237979
2002
2002
Cyclic AMP and cyclic GMP activate protein kinase G in cavernosal smooth muscle cells: old age is a negative factor
C. Lin
,
X. Liu
,
S. Chow
,
T. Lue
BJU International
2002
Corpus ID: 23191495
Objective To investigate protein kinase G‐I (PKG‐I) expression and activation in cavernosal smooth muscle cells (CSMC) of young…
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1999
1999
Chemically induced, activity-independent LTD elicited by simultaneous activation of PKG and inhibition of PKA.
Linda A. Santschi
,
M. Reyes-Harde
,
P. Stanton
Journal of Neurophysiology
1999
Corpus ID: 16580075
Although it is widely agreed that cyclic AMP is necessary for the full expression of long-term potentiation of synaptic strength…
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1996
1996
Effect of PKG activation on recombinant GABAA receptors.
N. Leidenheimer
Brain Research. Molecular Brain Research
1996
Corpus ID: 36872598
1992
1992
cGMP-dependent protein kinase regulation of a chloride channel in T84 cells.
M. Lin
,
A. Nairn
,
S. Guggino
American Journal of Physiology
1992
Corpus ID: 22044646
Chloride channels at the apical membrane of intestinal epithelial cells are involved in the excessive fluid secretion in diarrhea…
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