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PKG activity

Known as: cGMP-dependent protein kinase ibeta activity, PKG, 3':5'-cyclic GMP-dependent protein kinase activity 
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP. [GOC:mah]
National Institutes of Health

Papers overview

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2011
2011
Inappropriate signaling conditions within bone marrow stromal cells (BMSCs) can lead to loss of BMSC survival, contributing to… Expand
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2011
Highly Cited
2011
Background: Estrogens prevent bone loss in part by preventing osteocyte apoptosis. Results: Anti-apoptotic effects of 17… Expand
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2010
Highly Cited
2010
Nitric oxide (NO) and B-type natriuretic peptide (BNP) are protective against ischemia–reperfusion injury as they increase… Expand
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Highly Cited
2009
Highly Cited
2009
Photoreceptor degeneration in retinitis pigmentosa is one of the leading causes of hereditary blindness in the developed world… Expand
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2008
Highly Cited
2008
Recent studies have shown that nitric oxide (NO) signaling plays a crucial role in memory consolidation of Pavlovian fear… Expand
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Highly Cited
2004
Highly Cited
2004
We examined whether cGMP-dependent protein kinase (PKG) and mitochondrial ATP-sensitive potassium (K(ATP)) channels are involved… Expand
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Highly Cited
2003
Highly Cited
2003
The role of RhoA in myosin light-chain (MLC)(20) dephosphorylation and smooth muscle relaxation by PKA and PKG was examined in… Expand
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Highly Cited
2003
Highly Cited
2003
The vasodilator-stimulated phosphoprotein (VASP) plays an important role in cGMP-induced platelet inhibition. Since VASP is an in… Expand
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Highly Cited
2002
Highly Cited
2002
Nitric oxide (NO) can directly modulate cardiac contractility by accelerating relaxation and reducing diastolic tone. The… Expand
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Highly Cited
2002
Highly Cited
2002
NO acting through soluble guanylyl cyclase and cGMP formation is a negative regulator of cardiomyocyte hypertrophy. Downstream… Expand
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