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Cyclic GMP-Dependent Protein Kinases

Known as: Kinases, cGMP-Dependent Protein, Protein Kinases, cGMP-Dependent, Guanosine Cyclic 3',5' Phosphate Dependent Protein Kinase 
A group of cyclic GMP-dependent enzymes that catalyze the phosphorylation of SERINE or THREONINE residues of proteins.
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Over the past decade, myocardial structure, cardiomyocyte function, and intramyocardial signaling were shown to be specifically… Expand
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Highly Cited
2012
Highly Cited
2012
Hydrogen sulfide (H2S) is a unique gasotransmitter, with regulatory roles in the cardiovascular, nervous, and immune systems… Expand
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Highly Cited
2012
Highly Cited
2012
Background— Prominent features of myocardial remodeling in heart failure with preserved ejection fraction (HFPEF) are high… Expand
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Highly Cited
2010
Highly Cited
2010
Increased cyclic GMP from enhanced synthesis or suppressed catabolism (e.g. PDE5 inhibition by sildenafil, SIL) activates protein… Expand
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Highly Cited
2006
Highly Cited
2006
Cyclic GMP-dependent protein kinases protein kinase G (PKG) Iα and PKGIβ are major mediators of cGMP signaling in the… Expand
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Highly Cited
2005
Highly Cited
2005
Ischemic and pharmacological preconditioning can be triggered by an intracellular signaling pathway in which Gi-coupled surface… Expand
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Highly Cited
2004
Highly Cited
2004
Bradykinin (BK) mimics ischemic preconditioning by generating reactive oxygen species (ROS). To identify intermediate steps that… Expand
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Highly Cited
2003
Highly Cited
2003
ABSTRACT To test the hypothesis that the phosphatidylinositol 3-kinase (PI3 kinase)/protein kinase Akt signaling pathway is… Expand
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Highly Cited
2000
Highly Cited
2000
The bioactivity of endothelium-derived nitric oxide (NO) reflects its rates of production and of inactivation by superoxide (O(2… Expand
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Highly Cited
1999
Highly Cited
1999
NO-induced activation of cGMP-dependent protein kinase (PKG) increases the open probability of large conductance Ca2+-activated K… Expand
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