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PIK3C3 gene

Known as: phosphatidylinositol 3-kinase catalytic subunit type 3, VPS34, YEAST, HOMOLOG OF, PHOSPHATIDYLINOSITOL 3-KINASE, CLASS 3 
This gene plays a role in autophagosome formation and transport to lysosomes and late endosomes.
National Institutes of Health

Related topics

Related topics

10 relations
AutophagyClass III Phosphatidylinositol 3-Kinase Catalytic SubunitCytokinesisImmune response

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells.
2014
2014
Differential DNA methylation status between breast carcinomatous and normal tissues.
2012
2012
Mammalian PIK3C3/VPS34
PIK3C3/Vps34 is the class III PtdIns3K that is evolutionarily conserved from yeast to mammals. Its central role in mammalian… 
2012
2012
Vps34p Is Required for the Decline of Extracellular Fructose-1,6-bisphosphatase in the Vacuole Import and Degradation Pathway*
Background: Gluconeogenic enzymes are degraded in the vacuole via the Vid pathway during glucose re-feeding. Results: Fructose-1… 
2009
2009
Structure and function of Vps15 in the endosomal G protein signaling pathway.
G protein-coupled receptors mediate cellular responses to a wide variety of stimuli, including taste, light, and… 
Highly Cited
2007
Highly Cited
2007
Five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemia
BackgroundThe t(12;21)(p13;q22) translocation is found in 20 to 25% of cases of childhood B-lineage acute lymphoblastic leukemia… 
2005
2005
Analysis of PIK3C3 promoter variant in African-Americans with schizophrenia
2000
2000
Characterization of staurosporine-sensitive mutants of Saccharomyces cerevisiae: vacuolar functions affect staurosporine sensitivity
Abstract Mutations at several loci affect the sensitivity of the yeast Saccharomyces cerevisiae to staurosporine. We report here… 
Highly Cited
1995
Highly Cited
1995
A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development
Three groups of phosphatidylinositol (PI) kinases convert PI into PI(3)phosphate, PI(4)phosphate, PI(4,5) bisphosphate, and PI(3… 
1994
1994
Mammalian phosphatidylinositol 3'-kinase induces a lethal phenotype on expression in Schizosaccharomyces pombe; comparison with the VPS34 gene product.
The 110-kDa catalytic subunit of the phosphatidylinositol 3'-kinase (p110) is shown to be expressed in Schizosaccharomyces pombe… 
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