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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
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An approach to the analysis of design protocols
Abstract Little research has been done on how designers actually design. Much of design research is concerned with computer-based models or is based on anecdotal evidence of the design process. ThisExpand
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Understanding conceptual electronic design using protocol analysis
Some hypotheses about the design process, derived from the literature, are objectively tested using protocol analyses of various electronics designers engaged in conceptual design. Expand
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Curriculum Infusion as College Student Mental Health Promotion Strategy
This article describes efforts to increase faculty involvement in suicide prevention and mental health promotion via curriculum infusion. The participants were faculty, staff, and 659 studentsExpand
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EphA2 is a functional receptor for the growth factor progranulin
The receptor for the growth factor progranulin has remained unclear. Neill et al. show that the Ephrin receptor tyrosine kinase EphA2 is a functional signaling receptor for progranulin and mediatesExpand
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Decorin: a guardian from the matrix.
Decorin, an archetypal member of the small leucine-rich proteoglycan gene family, has a broad binding repertoire that encompasses matrix structural components, such as collagens, and growth factors,Expand
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Decorin Antagonizes the Angiogenic Network
Background: Decorin antagonizes multiple receptor tyrosine kinases, such as Met, to suppress tumorigenesis. Results: Decorin promotes angiostasis by blocking hypoxia inducible factor-1α and β-cateninExpand
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Decorin causes autophagy in endothelial cells via Peg3
Significance We identified a function for a member of the extracellular matrix in the regulation of autophagy. Decorin, a member of the small leucine-rich proteoglycan family and an establishedExpand
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Instructive roles of extracellular matrix on autophagy.
Autophagy plays an essential role in maintaining an intricate balance between nutrient demands and energetic requirements during normal homeostasis. Autophagy recycles metabolic substrates fromExpand
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Endorepellin Evokes Autophagy in Endothelial Cells*
Background: Endorepellin inhibits angiogenesis by simultaneously binding the α2β1 integrin and VEGFR2, attenuating the PI3K/Akt/mTOR and PKC/JNK/AP1 signaling pathways. Results: Endorepellin evokesExpand
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