PICALM gene

Known as: CLATHRIN ASSEMBLY LYMPHOID-MYELOID LEUKEMIA GENE, LAP, DROSOPHILA, HOMOLOG OF, phosphatidylinositol binding clathrin assembly protein 
This gene plays a role in receptor mediated endocytosis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
0102019902017

Papers overview

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2014
2014
Genome-wide association studies have identified several loci associated with Alzheimer's disease (AD), including proteins… (More)
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Highly Cited
2011
Highly Cited
2011
The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association study of late-onset Alzheimer disease using… (More)
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2011
2011
Recent genome-wide association studies have identified 5 loci (BIN1, CLU, CR1, EXOC3L2, and PICALM) as genetic determinants of… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVES To identify novel loci for late-onset Alzheimer disease (LOAD) in Caribbean Hispanic individuals and to replicate the… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVES To determine whether genotypes at CLU, PICALM, and CR1 confer risk for Alzheimer disease (AD) and whether risk for AD… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE To test for replication of the association between variants in the CLU, CR1, and PICALM genes with Alzheimer disease… (More)
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Highly Cited
2010
Highly Cited
2010
CONTEXT Genome-wide association studies (GWAS) have recently identified CLU, PICALM, and CR1 as novel genes for late-onset… (More)
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Highly Cited
2010
Highly Cited
2010
In this study, we assess 34 of the most replicated genetic associations for Alzheimer's disease (AD) using data generated on… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE To identify cognitively normal individuals at risk of Alzheimer disease (AD) based on cerebrospinal fluid (CSF) Aβ1-42… (More)
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Highly Cited
2009
Highly Cited
2009
The gene encoding apolipoprotein E (APOE) on chromosome 19 is the only confirmed susceptibility locus for late-onset Alzheimer's… (More)
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